Scianowski J, Kedziora J, Zolynski K
Department of Radiological Protection and Toxicology, Military Medical Academy, Lodz, Poland.
Int J Occup Med Environ Health. 1995;8(4):315-19.
The investigations were carried out on 20 men (aged 32-48), hospitalized after lower extremity fractures, in whom no systemic diseases or disorders were found. The activity of glucose-6-phosphate dehydrogenase (G6P-DH), aldolase (A1), lactate dehydrogenase (LDH) and the concentrations of pyruvate, lactate, nicotinamide-adenine dinucleotide (NAD), nicotinamideadenine dinucleotide phosphate (NADP), adenosine-5'-triphosphate (ATP), adenosine-5'-diphosphate (ADP), adenosine -5'-monophosphate (AMP) and 2,3-diphosphoglycerate (2,3-DPG) in erythrocytes taken from patients were estimated. After a two-week hypokinesia G6P-DH, A1, LDH activities and ATP, ADP, AMP concentrations decreased, whereas other estimated parameters did not differ from the control levels. During a 30-day hypokinesia of patients with fractures of the lower extremity a transient decrease of erythrocyte metabolic activity was observed after two weeks. off
对20名男性（年龄在32 - 48岁之间）进行了调查，这些男性因下肢骨折住院，未发现全身性疾病或功能紊乱。对取自患者的红细胞中的葡萄糖-6-磷酸脱氢酶（G6P-DH）、醛缩酶（A1）、乳酸脱氢酶（LDH）的活性以及丙酮酸、乳酸、烟酰胺腺嘌呤二核苷酸（NAD）、烟酰胺腺嘌呤二核苷酸磷酸（NADP）、腺苷-5'-三磷酸（ATP）、腺苷-5'-二磷酸（ADP）、腺苷-5'-单磷酸（AMP）和2,3-二磷酸甘油酸（2,3-DPG）的浓度进行了评估。经过两周的运动不足，G6P-DH、A1、LDH活性以及ATP、ADP、AMP浓度降低，而其他评估参数与对照水平无差异。在下肢骨折患者30天的运动不足期间，两周后观察到红细胞代谢活性短暂下降。 关闭
