Barriga C, Pombero I, Duran J, Forner A, Cardesa J, Rodriguez A B
Departamento de Fisiologia (Animal), Facultad de Ciencias Univeridad de Extremadura, Badajoz, Spain.
Rev Esp Fisiol. 1995 Dec;51(4):213-8.
Whether formula or breast feeding influences the functional activity of the complement system from birth to three months of age has been studied. The classical pathway was evaluated by assessing hemolytic activity, based on the capacity of the intact complement system to lyse sheep erythrocytes when coated with specific antibodies. The bactericidal activity of the serum against Staphylococcus aureus and Escherichia coli was used to evaluate the alternative complement pathway. Sera were obtained from neonates (40 +/- 2 weeks of gestation), and one-month or three-month old infants, fed either breast or formula. Control serum was obtained from healthy adults between 22 and 30 years of age. The hemolytic capacity of serum from breast-fed infants of one month and three months of age was significantly greater than that of the serum from infants which had been fed formula milk.
配方奶喂养或母乳喂养对出生至三个月龄婴儿补体系统功能活性的影响已得到研究。经典途径通过评估溶血活性来评价，该活性基于完整补体系统在包被特异性抗体时裂解绵羊红细胞的能力。血清对金黄色葡萄球菌和大肠杆菌的杀菌活性用于评估替代补体途径。从新生儿（妊娠40±2周）、1个月或3个月大的婴儿获取血清，这些婴儿分别采用母乳喂养或配方奶喂养。对照血清取自22至30岁的健康成年人。1个月和3个月大的母乳喂养婴儿血清的溶血能力显著高于配方奶喂养婴儿的血清。
