Suzuki K, Nishiyama Y, Sugiyama K, Miyamoto N, Baba S
Department of Otolaryngology, Nagoya City University Medical School, Japan.
Acta Otolaryngol Suppl. 1996;525:51-5.
Trends in the detection of causative pathogens and changes in bacterial counts in patients with sinusitis treated between January 1989 and December 1993 were investigated. In adult patients with chronic sinusitis, Staphylococcus aureus (S. aureus), coagulase negative staphylococci (CNS), Streptococcus pneumoniae (S. pneumoniae), Corynebacterium sp., Haemophilus influenzae (H. influenzae), and Moraxella catarrhalis were often isolated while Pseudomonas aeruginosa (P. aeruginosa) and anaerobic bacteria were detected in 2.4% and 5.3% of patients, respectively. The bacteria isolated from adult patients with acute sinusitis and pediatric patients with either acute or chronic sinusitis were somewhat different from those of adult chronic sinusitis. No bacteria could be isolated from 5.8% of adult chronic sinusitis patients, 8.1% of adult acute sinusitis patients, and 3.1% of pediatric sinusitis patients. The detection rate for anaerobic bacteria has been rising in chronic sinusitis patients owing to improved detection techniques in recent years, while there has been no appreciable change in the isolation rate for other types of bacteria. When the pathogenicity of isolated bacteria was determined based on the amount of bacterial colonization it was found that P. aeruginosa, S. pneumoniae, H. influenzae, and S. aureus were significant as causative pathogens in sinusitis, while CNS.
对1989年1月至1993年12月期间接受治疗的鼻窦炎患者中致病病原体的检测趋势以及细菌计数变化进行了调查。在成年慢性鼻窦炎患者中，经常分离出金黄色葡萄球菌、凝固酶阴性葡萄球菌、肺炎链球菌、棒状杆菌属、流感嗜血杆菌和卡他莫拉菌，而铜绿假单胞菌和厌氧菌分别在2.4%和5.3%的患者中被检测到。从成年急性鼻窦炎患者以及患有急性或慢性鼻窦炎的儿科患者中分离出的细菌与成年慢性鼻窦炎患者的有所不同。5.8%的成年慢性鼻窦炎患者、8.1%的成年急性鼻窦炎患者和3.1%的儿科鼻窦炎患者未分离出细菌。由于近年来检测技术的改进，慢性鼻窦炎患者中厌氧菌的检出率一直在上升，而其他类型细菌的分离率没有明显变化。当根据细菌定植量确定分离出的细菌的致病性时，发现铜绿假单胞菌、肺炎链球菌、流感嗜血杆菌和金黄色葡萄球菌作为鼻窦炎的致病病原体具有重要意义，而凝固酶阴性葡萄球菌…… （原文此处不完整）
