Murata K, Shiraki K, Takase K, Nakano T, Tameda Y
First Department of Internal Medicine, Mie University School of Medicine.
Hepatogastroenterology. 1996 Sep-Oct;43(11):1212-7.
BACKGROUND/AIMS: Fifteen cases of liver cirrhosis (LC) were examined to determine whether the partial splenic embolization (PSE), done to improve hematological disorders, could also improve liver function for at least 12 months.
Peripheral blood count, serological and coagulatory examination were retrospectively examined before PSE, 6 months and 12 months after PSE.
Hematological disorders were improved (p < 0.01) and persisted at improved levels in all cases. In patients in Child A or Child B classification, the levels of cholinesterase, total cholesterol and prothrombin time were also improved significantly after PSE (p < 0.05). However, those parameters were not improved in Child C classification.
PSE may improve not only hematological disorders but also liver functions for at least one year.
背景/目的:对15例肝硬化(LC)患者进行检查,以确定为改善血液系统疾病而进行的部分脾栓塞术(PSE)是否也能在至少12个月内改善肝功能。
回顾性分析PSE术前、术后6个月和12个月的外周血细胞计数、血清学和凝血检查结果。
所有病例的血液系统疾病均得到改善(p < 0.01),且维持在改善水平。Child A或Child B分级的患者,PSE术后胆碱酯酶、总胆固醇和凝血酶原时间水平也显著改善(p < 0.05)。然而,Child C分级的患者这些参数未得到改善。
PSE不仅可以改善血液系统疾病,还可以在至少一年内改善肝功能。