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Cytolytic T lymphocyte responses of cancer patients to tumor-associated antigens.

作者信息

Romero P

机构信息

Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, Epalinges, Switzerland.

出版信息

Springer Semin Immunopathol. 1996;18(2):185-98. doi: 10.1007/BF00820665.

DOI:10.1007/BF00820665
PMID:8908699
Abstract
摘要

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Cytolytic T lymphocyte responses of cancer patients to tumor-associated antigens.
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Recognition of tumor-associated antigens by T lymphocytes: from basic concepts to new approaches.T淋巴细胞对肿瘤相关抗原的识别：从基本概念到新方法
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Antigens recognized on human tumors by cytolytic T lymphocytes: towards vaccination?细胞毒性T淋巴细胞识别的人类肿瘤抗原：用于疫苗接种？
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引用本文的文献

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High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.在很大比例的人类组织相容性白细胞抗原（HLA）-A2个体中，幼稚型黑色素瘤抗原A/MART-1特异性CD8(+) T细胞的频率很高。
J Exp Med. 1999 Sep 6;190(5):705-15. doi: 10.1084/jem.190.5.705.
2
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes.通过I类主要组织相容性复合体四聚体对转移性淋巴结进行体外染色，发现大量经历过抗原刺激的肿瘤特异性细胞溶解T淋巴细胞。
J Exp Med. 1998 Nov 2;188(9):1641-50. doi: 10.1084/jem.188.9.1641.

本文引用的文献

1
A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma.一种编码人类肾癌上被自体细胞溶解性T淋巴细胞识别的抗原的新基因。
Immunogenetics. 1996;44(5):323-30. doi: 10.1007/BF02602776.
2
HLA photoaffinity labeling reveals overlapping binding of homologous melanoma-associated gene peptides by HLA-A1, HLA-A29, and HLA-B44.HLA光亲和标记揭示了同源黑色素瘤相关基因肽与HLA - A1、HLA - A29和HLA - B44的重叠结合。
J Biol Chem. 1996 May 24;271(21):12463-71. doi: 10.1074/jbc.271.21.12463.
3
Infrequent expression of the MAGE gene family in uveal melanomas.
黑色素瘤相关抗原（MAGE）基因家族在葡萄膜黑色素瘤中表达稀少。
Int J Cancer. 1996 Jun 11;66(6):738-42. doi: 10.1002/(SICI)1097-0215(19960611)66:6<738::AID-IJC5>3.0.CO;2-0.
4
A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes.一种突变的β-连环蛋白基因编码一种被肿瘤浸润淋巴细胞识别的黑色素瘤特异性抗原。
J Exp Med. 1996 Mar 1;183(3):1185-92. doi: 10.1084/jem.183.3.1185.
5
A peptide recognized by human cytolytic T lymphocytes on HLA-A2 melanomas is encoded by an intron sequence of the N-acetylglucosaminyltransferase V gene.一种在HLA - A2黑色素瘤上被人细胞溶解性T淋巴细胞识别的肽由N - 乙酰葡糖胺基转移酶V基因的一个内含子序列编码。
J Exp Med. 1996 Mar 1;183(3):1173-83. doi: 10.1084/jem.183.3.1173.
6
Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen.利用正常基因的一个替代开放阅读框来产生一种新型人类癌症抗原。
J Exp Med. 1996 Mar 1;183(3):1131-40. doi: 10.1084/jem.183.3.1131.
7
Identification of clonally expanded T cells in rheumatoid arthritis using a sequence enrichment nuclease assay.使用序列富集核酸酶分析鉴定类风湿性关节炎中克隆性扩增的T细胞。
J Clin Invest. 1996 Mar 1;97(5):1335-43. doi: 10.1172/JCI118550.
8
Recurrent T cell receptor rearrangements in the cytotoxic T lymphocyte response in vivo against the p815 murine tumor.体内针对p815小鼠肿瘤的细胞毒性T淋巴细胞反应中的复发性T细胞受体重排。
J Exp Med. 1996 Feb 1;183(2):439-49. doi: 10.1084/jem.183.2.439.
9
A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3.
Immunogenetics. 1996;43(6):377-83. doi: 10.1007/BF02199806.
10
Generation of cytotoxic T-cell responses with synthetic melanoma-associated peptides in vivo: implications for tumor vaccines with melanoma-associated antigens.体内用合成的黑色素瘤相关肽产生细胞毒性T细胞反应：对含黑色素瘤相关抗原的肿瘤疫苗的意义。
Int J Cancer. 1996 Apr 10;66(2):162-9. doi: 10.1002/(SICI)1097-0215(19960410)66:2<162::AID-IJC4>3.0.CO;2-0.