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用于引导组织再生(GTR)和引导骨组织再生(GBR)应用的可生物降解和可生物吸收聚合物及装置的材料特性综述。

A review of material properties of biodegradable and bioresorbable polymers and devices for GTR and GBR applications.

作者信息

Hutmacher D, Hürzeler M B, Schliephake H

机构信息

Department of Biomechanics, Polytecnic Offenburg, Germany.

出版信息

Int J Oral Maxillofac Implants. 1996 Sep-Oct;11(5):667-78.

PMID:8908867
Abstract

Use of bioresorbable and biodegradable materials for guided tissue and guided bone regeneration is under intense investigation and is being tested in clinical trials. This study presents a basic overview of material properties of bioresorbable and biodegradable polymers and devices for guided tissue and guided bone regeneration treatment. Collagens and aliphatic polyesters, such as poly(glycolic acid), poly(lactic acid), and poly(epsilon-caprolactone), are discussed, as well as biocompatibility, mechanical properties, and sterilization.

摘要

生物可吸收和可生物降解材料在引导组织再生和引导骨再生中的应用正在深入研究,并正在临床试验中进行测试。本研究概述了用于引导组织再生和引导骨再生治疗的生物可吸收和可生物降解聚合物及装置的材料特性。文中讨论了胶原蛋白和脂肪族聚酯,如聚乙醇酸、聚乳酸和聚己内酯,以及生物相容性、机械性能和灭菌情况。

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