Ford T R, Torabinejad M, Abedi H R, Bakland L K, Kariyawasam S P
Department of Conservative Dentistry, United Medical School, Guy's Hospital, University of London, England.
J Am Dent Assoc. 1996 Oct;127(10):1491-4. doi: 10.14219/jada.archive.1996.0058.
This study examined the dental pulp responses in monkeys to mineral trioxide aggregate, or MTA, and a calcium hydroxide preparation when used as pulp-capping materials. After the pulps of 12 mandibular incisors were exposed with a No. 1 round bur, they were capped with either MTA or the calcium hydroxide preparation. After five months, the authors noted no pulpal inflammation in five of six samples capped with MTA, and all six pulps in this group had a complete dentin bridge. In contrast, all of the pulps capped with the calcium hydroxide preparation showed pulpal inflammation, and bridge formation occurred in only two samples. Based on these results, it appears that MTA has the potential to be used as a pulp-capping material during vital pulp therapy.
本研究检测了猴牙髓对用作盖髓材料的三氧化矿物凝聚体（MTA）和氢氧化钙制剂的反应。在用1号圆钻暴露12颗下颌切牙的牙髓后，用MTA或氢氧化钙制剂进行盖髓。五个月后，作者发现，在六个用MTA盖髓的样本中，有五个没有牙髓炎症，且该组的所有六个牙髓都形成了完整的牙本质桥。相比之下，所有用氢氧化钙制剂盖髓的牙髓都出现了牙髓炎症，只有两个样本形成了桥。基于这些结果，MTA似乎有潜力在活髓治疗中用作盖髓材料。
