Institute of Dentistry, Route de l'Université, University Cheikh Anta Diop, Dakar, Senegal.
Int Dent J. 2012 Feb;62(1):33-9. doi: 10.1111/j.1875-595X.2011.00084.x.
To assess the effectiveness of mineral trioxide aggregate (MTA) used as an indirect pulp-capping material in human molar and premolar teeth.
We conducted a clinical evaluation of 60 teeth, which underwent an indirect pulp-capping procedure with either MTA or calcium hydroxide cement (Dycal(®) ). Calcium hydroxide was compared with MTA and the thickness of the newly formed dentine was measured at regular time intervals. The follow-up was at 3 and 6 months, and dentine formation was monitored by radiological measurements on digitised images using Mesurim Pro(®) software.
At 3 months, the clinical success rates of MTA and calcium hydroxide were 93% and 73%, respectively (P = 0.02). At 6 months, the success rate was 89.6% with MTA, and remained steady at 73% with calcium hydroxide (P = 0.63). The mean initial residual dentine thickness was 0.23 mm, and increased by 0.121 mm with MTA and by 0.136 mm with calcium hydroxide at 3 months. At 6 months, there was an increase of 0.235 mm with MTA and of 0.221 mm with calcium hydroxide.
A higher success rate was observed in the MTA group relative to the Dycal(®) group after 3 months, which was statistically significant. After 6 months, no statistically significant difference was found in the dentine thickness between the two groups. Additional histological investigations are needed to support these findings.
评估三氧化矿物凝聚体（MTA）作为人磨牙和前磨牙间接盖髓材料的有效性。
我们对 60 颗牙齿进行了临床评估，这些牙齿采用 MTA 或氢氧化钙水泥（Dycal(®)）进行间接盖髓。将氢氧化钙与 MTA 进行比较，并在定期时间间隔测量新形成的牙本质的厚度。随访时间为 3 个月和 6 个月，使用 Mesurim Pro(®)软件通过数字化图像的放射学测量来监测牙本质的形成。
在 3 个月时，MTA 和氢氧化钙的临床成功率分别为 93%和 73%（P=0.02）。在 6 个月时，MTA 的成功率为 89.6%，而氢氧化钙的成功率保持在 73%（P=0.63）。初始残余牙本质厚度的平均值为 0.23mm，MTA 增加了 0.121mm，氢氧化钙增加了 0.136mm。在 6 个月时，MTA 增加了 0.235mm，而氢氧化钙增加了 0.221mm。
在 3 个月时，MTA 组的成功率高于 Dycal(®)组，这具有统计学意义。6 个月后，两组之间牙本质厚度无统计学差异。需要进行额外的组织学研究来支持这些发现。
