双胎妊娠所致皮质视觉障碍
Cortical visual impairment caused by twin pregnancy.
作者信息
Good W V, Brodsky M C, Angtuaco T L, Ferriero D M, Stephens D C, Khakoo Y
机构信息
Department of Ophthalmology, University of Cincinnati Medical Center, Ohio 45267-0527, USA.
出版信息
Am J Ophthalmol. 1996 Nov;122(5):709-16. doi: 10.1016/s0002-9394(14)70491-x.
PURPOSE
To report a possible relationship between twin pregnancy and cortical visual impairment.
METHODS
Three children who had been the products of twin pregnancies were identified as having cortical visual impairment. One child (Patient 2), a dizygotic twin, developed cortical visual impairment after a preterm birth. Two children (Patients 1 and 3), the products of monochorionic pregnancies, developed cortical visual impairment. All children were examined ophthalmologically and neurologically.
RESULTS
An evaluation of the gestations of these children indicates that twin pregnancy per se was probably etiologic in the development of cortical visual impairment. In Patient 2, twin pregnancy probably caused preterm birth and resulting cortical visual impairment. In Patients 1 and 3, twin-to-twin transfusion syndrome was the cause of cortical visual impairment. In Patient 1, fetal demise precipitated an acute twin-to-twin transfusion syndrome.
CONCLUSIONS
Children who show cortical visual impairment at or shortly after birth should be evaluated for the possibility of twin pregnancy. Twin pregnancy increases the risk of neurologic damage, including damage to the visual cortex, to optic radiations, or both.
目的
报告双胎妊娠与皮质视觉障碍之间可能存在的关系。
方法
三名双胎妊娠产物被诊断为患有皮质视觉障碍。一名儿童（患者2），为双卵双胎，早产之后出现皮质视觉障碍。两名儿童（患者1和患者3），为单绒毛膜双胎妊娠产物，患有皮质视觉障碍。所有儿童均接受了眼科和神经科检查。
结果
对这些儿童孕期情况的评估表明，双胎妊娠本身可能是皮质视觉障碍发病的病因。在患者2中，双胎妊娠可能导致早产，进而引发皮质视觉障碍。在患者1和患者3中，双胎输血综合征是皮质视觉障碍的病因。在患者1中，一胎死亡引发了急性双胎输血综合征。
结论
对于出生时或出生后不久出现皮质视觉障碍的儿童，应评估其双胎妊娠的可能性。双胎妊娠会增加神经损伤的风险，包括对视皮质、视辐射或两者的损伤。
Zotero 插件