下丘脑-垂体发育不全作为无眼症中垂体激素缺乏的神经影像学关联
Hypothalamic-hypophyseal dysgenesis as a neuroimaging correlate of pituitary hormone deficiency in anophthalmia.
作者信息
Brodsky M C, Frindik J P
机构信息
Department of Ophthalmology, University of Arkansas for Medical Sciences, USA.
出版信息
Am J Ophthalmol. 1996 Nov;122(5):747-8. doi: 10.1016/s0002-9394(14)70505-7.
PURPOSE
To document the association of neurohypophyseal dysgenesis with hypopituitarism in a child with primary bilateral anophthalmia.
METHODS
An infant with bilateral anophthalmia underwent magnetic resonance imaging and endocrinologic evaluation.
RESULTS
Magnetic resonance imaging showed dysgenesis confined to the hypothalamus and hypophyseal stalk. Endocrinologic testing showed low serum cortisol and pituitary gonadotropin levels.
CONCLUSION
Magnetic resonance imaging can help predict which children with anophthalmia will have endocrinologic deficiencies.
目的
记录一名原发性双侧无眼患儿神经垂体发育不全与垂体功能减退之间的关联。
方法
一名双侧无眼婴儿接受了磁共振成像和内分泌学评估。
结果
磁共振成像显示发育不全局限于下丘脑和垂体柄。内分泌学检测显示血清皮质醇和垂体促性腺激素水平较低。
结论
磁共振成像有助于预测哪些无眼儿童会出现内分泌缺陷。
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