Anlar B, Saatçi I, Köse G, Yalaz K
Department of Pediatric Neurology, Hacettepe University, Ankara, Turkey.
Neurology. 1996 Nov;47(5):1278-83. doi: 10.1212/wnl.47.5.1278.
Thirty-four MRI studies of 26 patients with subacute sclerosing panencephalitis are reported. Lesions of high signal intensity on T2-weighted images are the most common finding; they frequently involve the periventricular or subcortical white matter. Lesions tend to start in the cortex-subcortical white matter and progress with periventricular white matter involvement and diffuse cerebral atrophy. Pial and parenchymal contrast enhancement, local mass effect of parenchymal lesions, and involvement of the splenic portion of the corpus callosum are not infrequent. Basal ganglia and brainstem lesions were rare in this series. Although cortical and subcortical lesions have some correlation with clinical findings, the extent and location of the periventricular white matter lesions and cerebral atrophy did not reflect the neurologic status in many patients.
报告了对26例亚急性硬化性全脑炎患者进行的34项MRI研究。T2加权图像上高信号强度病变是最常见的发现；它们常累及脑室周围或皮质下白质。病变往往始于皮质-皮质下白质，并随着脑室周围白质受累和弥漫性脑萎缩而进展。软脑膜和实质对比增强、实质病变的局部占位效应以及胼胝体脾部受累并不少见。在本系列中，基底节和脑干病变很少见。虽然皮质和皮质下病变与临床发现有一定相关性，但在许多患者中，脑室周围白质病变的范围和位置以及脑萎缩并未反映神经状态。
