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移植肝中的肿瘤性肝内淋巴细胞增殖性疾病

Tumorous intrahepatic lymphoproliferative disorder in transplanted livers.

作者信息

Strouse P J, Platt J F, Francis I R, Bree R L

机构信息

Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109-0252, USA.

出版信息

AJR Am J Roentgenol. 1996 Nov;167(5):1159-62. doi: 10.2214/ajr.167.5.8911173.

DOI:10.2214/ajr.167.5.8911173
PMID:8911173
Abstract

OBJECTIVE

We describe the radiologic findings of lymphoproliferative disorder manifesting as an intrahepatic mass in hepatic transplant recipients. Three patients with focal intrahepatic masses due to lymphoproliferative disorder after transplantation were retrospectively identified. Clinical features and radiologic findings in these patients were reviewed in conjunction with pertinent cases from the literature. (Reports of lymphoproliferative disorder confined to the transplanted liver have been sporadic.)

CONCLUSION

Factors supporting the diagnosis of tumorous intrahepatic lymphoproliferative disorder include presentation 4-12 months after transplantation; portal or periportal location; poorly defined extrahepatic periportal soft tissue; encasement or narrowing of the biliary ducts, hepatic artery, or portal vein; and serologic evidence of exposure to Epstein-Barr virus.

摘要

目的

我们描述了肝移植受者中表现为肝内肿块的淋巴增殖性疾病的影像学表现。回顾性确定了3例移植后因淋巴增殖性疾病导致局灶性肝内肿块的患者。结合文献中的相关病例,对这些患者的临床特征和影像学表现进行了回顾。(局限于移植肝脏的淋巴增殖性疾病的报道较为零散。)

结论

支持肝内肿瘤性淋巴增殖性疾病诊断的因素包括:移植后4 - 12个月出现;门静脉或门静脉周围位置;肝外门静脉周围软组织边界不清;胆管、肝动脉或门静脉受压包绕或狭窄;以及接触爱泼斯坦 - 巴尔病毒的血清学证据。

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Tumorous intrahepatic lymphoproliferative disorder in transplanted livers.移植肝中的肿瘤性肝内淋巴细胞增殖性疾病
AJR Am J Roentgenol. 1996 Nov;167(5):1159-62. doi: 10.2214/ajr.167.5.8911173.
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Pretransplantation seronegative Epstein-Barr virus status is the primary risk factor for posttransplantation lymphoproliferative disorder in adult heart, lung, and other solid organ transplantations.移植前血清学阴性的爱泼斯坦-巴尔病毒状态是成人心脏、肺及其他实体器官移植后淋巴增殖性疾病的主要危险因素。
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Abdom Radiol (NY). 2021 Jan;46(1):68-83. doi: 10.1007/s00261-020-02799-7. Epub 2020 Oct 12.
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Donor-derived Viral Infections in Liver Transplantation.肝移植中的供体来源病毒感染。
Transplantation. 2018 Nov;102(11):1824-1836. doi: 10.1097/TP.0000000000002326.
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Enlarged lymph nodes in the upper abdomen after liver transplantation: imaging features and clinical significance.肝移植后上腹部淋巴结肿大:影像学特征及临床意义。
Radiol Med. 2011 Oct;116(7):1067-75. doi: 10.1007/s11547-011-0690-9. Epub 2011 Jun 4.