Gupta R K
Department of Laboratory Services, Wellington Hospital and School of Medicine, New Zealand.
Cytopathology. 1996 Oct;7(5):352-6. doi: 10.1111/j.1365-2303.1996.tb00314.x.
Spherical ringlike structures of various sizes resembling Liesegang rings (LRs) are described in four fine needle aspirates (FNAs) from breast lesions over a period of 13 years. A characteristic finding in these structures was a distinct double layer outer wall with striations and an amorphous central nidus. Under polarized light they were non-refractile and no birefringence was noted in Congo red. Immunohistochemical stains for calcium, iron, mucus, glycogen, amyloid, cytokeratin and epithelial membrane antigen in all the cases were found to be negative. Since LRs can be mistaken for ova or parasites, their presence in aspirates of breast should be kept in mind to avoid misdiagnosis.
在13年的时间里，从乳腺病变的4份细针穿刺抽吸物（FNA）中发现了各种大小类似李塞根环（LRs）的球形环状结构。这些结构的一个特征性发现是有明显的双层外壁和条纹，以及一个无定形的中央核。在偏振光下，它们不折射，刚果红染色未发现双折射现象。所有病例中钙、铁、黏液、糖原、淀粉样蛋白、细胞角蛋白和上皮膜抗原的免疫组织化学染色均为阴性。由于LRs可能被误认为是卵子或寄生虫，因此在乳腺抽吸物中发现它们时应予以注意，以避免误诊。
