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倍半萜内酯在对某些南北美洲种类的小白菊(菊科银胶菊属)接触性超敏反应中的作用

The role of sesquiterpene lactones in contact hypersensitivity to some North and South American species of feverfew (Parthenium-Compositae).

作者信息

Rodríguez E, Epstein W L, Mitchell J C

出版信息

Contact Dermatitis. 1977 Jun;3(3):155-62. doi: 10.1111/j.1600-0536.1977.tb03632.x.

DOI:10.1111/j.1600-0536.1977.tb03632.x
PMID:891178
Abstract

Sixteen taxa of the genus Parthenium from North and South America and 20 sesquiterpene lactones derived from plants of the Compositae family were used for patch testing six volunteers who were known to be contact sensitive to plants and lactones of this family. The patterns of cross-sensitivity and structure-activity relationships of the allergenic lactones are evaluated and the clinical and ecological relevance is discussed.

摘要

来自北美洲和南美洲的16种银胶菊属分类群以及20种源自菊科植物的倍半萜内酯,被用于对6名已知对该科植物和内酯有接触性敏感的志愿者进行斑贴试验。评估了致敏内酯的交叉敏感性模式和构效关系,并讨论了其临床和生态学相关性。

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