Curković B, Babić-Naglić D, Durrigl T, Ivanisević G
Department for Rheumatic Diseases and Rehabilitation, Rebro, Zagreb.
Reumatizam. 1996;43(1):10-5.
Sixty patients with early diagnosed rheumatoid arthritis according ARA criteria were followed up for 6.6 years with the goal to determine prognosis. The parameters relevant to patient and physician were selected for follow up. Radiological and functional deterioration was evident after 6.6 years in 3/4 of patients and there was no one of them to satisfy remission criteria. The most unfavourable predictor of final outcome was the degree of functional incapacity in early stage of rheumatoid arthritis. Second important predictor of poor prognosis was degree of radiological destructive changes especially on feet. Poor prognosis could be expected in patients with previous attacks and the beginning of disease in elderly age. General symptoms and affection of mesomelic joints can be also undesirable predictor. Sex, morning stiffness, joint pattern, laboratory findings and rheumatoid factor were not significant predictors for prognosis but they could influence certain variables of global assessment.
根据美国风湿病学会（ARA）标准早期诊断为类风湿性关节炎的60例患者接受了6.6年的随访，目的是确定预后情况。选择了与患者和医生相关的参数进行随访。6.6年后，四分之三的患者出现明显的放射学和功能恶化，且无一例患者符合缓解标准。类风湿性关节炎早期功能丧失程度是最终结局最不利的预测因素。预后不良的第二个重要预测因素是放射学破坏改变的程度，尤其是足部。既往有发作史且发病于老年的患者预后较差。全身症状和四肢中部关节受累也可能是不良预测因素。性别、晨僵、关节模式、实验室检查结果和类风湿因子对预后不是显著的预测因素，但它们可能影响整体评估的某些变量。
