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成年HIV患者中不寻常的犬小孢子菌感染。

Unusual Microsporum canis infections in adult HIV patients.

作者信息

Bournerias I, De Chauvin M F, Datry A, Chambrette I, Carriere J, Devidas A, Blanc F

机构信息

Department of Infectious Diseases, Hôpital de la Salpêtrière, Paris, France.

出版信息

J Am Acad Dermatol. 1996 Nov;35(5 Pt 2):808-10. doi: 10.1016/s0190-9622(96)90089-4.

DOI:10.1016/s0190-9622(96)90089-4
PMID:8912591
Abstract

Tinea capitis in men, even if infected with HIV, is infrequent. Microsporum species nail infections are extremely rare. In most cases Microsporum canis infection is usually easy to treat with antifungal agents. We describe two HIV-infected men with an unusual M. canis infection. Both patients had tinea capitis, presenting as alopecia in one and scaling of the scalp in the other. One patient also had tinea unguium caused by M. canis. Ketoconazole was ineffective in both patients; terbinafine was tried in one patient without benefit; itraconazole was effective in both, but treatment took many months and only one patient was cured.

摘要

男性头癣,即使感染了艾滋病毒,也不常见。小孢子菌属引起的指甲感染极为罕见。在大多数情况下,犬小孢子菌感染通常用抗真菌药物很容易治疗。我们描述了两名感染艾滋病毒的男性患有不寻常的犬小孢子菌感染。两名患者均患有头癣,其中一名表现为脱发,另一名表现为头皮脱屑。一名患者还患有由犬小孢子菌引起的甲癣。酮康唑对两名患者均无效;对一名患者试用了特比萘芬但无效果;伊曲康唑对两人均有效,但治疗持续了数月,只有一名患者治愈。

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Unusual Microsporum canis infections in adult HIV patients.成年HIV患者中不寻常的犬小孢子菌感染。
J Am Acad Dermatol. 1996 Nov;35(5 Pt 2):808-10. doi: 10.1016/s0190-9622(96)90089-4.
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The use of itraconazole to treat cutaneous fungal infections in children.伊曲康唑用于治疗儿童皮肤真菌感染。
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Itraconazole in the treatment of tinea capitis caused by Microsporum canis: experience in a large cohort.伊曲康唑治疗犬小孢子菌引起的头癣:一项大型队列研究的经验
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Selection and validation of reference genes for qRT-PCR analysis of gene expression in Microsporum canis growing under different adhesion-inducing conditions.选择和验证用于 qRT-PCR 分析不同诱导黏附条件下生长的犬小孢子菌基因表达的内参基因。
Sci Rep. 2018 Jan 19;8(1):1197. doi: 10.1038/s41598-018-19680-9.
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Pathogenic fungus Microsporum canis activates the NLRP3 inflammasome.致病性真菌犬小孢子菌激活NLRP3炎性小体。
Infect Immun. 2014 Feb;82(2):882-92. doi: 10.1128/IAI.01097-13. Epub 2013 Dec 9.
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Microsporum spp. onychomycosis: disease presentation, risk factors and treatment responses in an urban population.
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Tinea capitis in the form of concentric rings in an HIV positive adult on antiretroviral treatment.一名接受抗逆转录病毒治疗的HIV阳性成年患者出现呈同心圆状的头癣。
Indian J Dermatol. 2012 Jul;57(4):288-90. doi: 10.4103/0019-5154.97672.
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Immunoprophylaxis of dermatophytosis in animals.动物皮肤癣菌病的免疫预防
Mycopathologia. 2008 Nov-Dec;166(5-6):407-24. doi: 10.1007/s11046-008-9111-6. Epub 2008 May 14.