Woodley D, Chambers W, Starke H, Dzindzio B, Forker A D
Chest. 1977 Sep;72(3):369-72. doi: 10.1378/chest.72.3.369.
A 24-year-old white man had a history of "epilepsy" since the age of eight years. Prolapse of the mitral valve was documented by auscultation and echocardiographic and left ventriculographic studies. At 120 hours after stopping therapy with phenobarbital and diphenylhydantoin (Dilantin) sodium, continuous electrocardiographic monitoring (Holter monitor) revealed episodes of complete atrioventricular block lasting up to 23 seconds. The results of hemodynamic studies were normal. The patients' symptoms were all totally corrected by implantation of an epicardial demand pacemaker. This report raises the possibility that sudden death in association with the mitral valve prolapse syndrome may be due to intermittent severe disturbances in conduction, in addition to ventricular arrhythmias.
一名24岁的白人男性自8岁起就有“癫痫”病史。通过听诊、超声心动图和左心室造影检查证实有二尖瓣脱垂。在停用苯巴比妥和苯妥英钠（大仑丁）钠治疗120小时后，连续心电图监测（动态心电图监测）显示出现完全性房室传导阻滞，持续时间长达23秒。血液动力学研究结果正常。通过植入心外膜按需起搏器，患者的所有症状均得到完全纠正。本报告提出，二尖瓣脱垂综合征相关的猝死除室性心律失常外，可能还归因于间歇性严重传导障碍。
