An introduction to guinea worm on the eve of its departure: dracunculiasis transmission, health effects, ecology and control.

A broad ranging discussion of the basic nature of guinea worm disease, fused with personal field observations in Ghana, shows its long-overlooked serious clinical aspects, and the many environmental and social influences that explain its persistence in the face of control efforts. It is a disease of neglect par excellence in remote rural areas. The global eradication campaign (which is not reviewed here) may be expected to come to closure over the next half decade. This account offers an overview, synthesis, and interpretation of a fascinating example in disease ecology at the time of its global vanishing.