肾嗜酸细胞瘤中的t(1;12)(p36;q13)
The t(1;12)(p36;q13) in a renal oncocytoma.
作者信息
Dal Cin P, Van Poppel H, Sciot R, De Vos R, Van Damme B, Baert L, Van den Berghe H
机构信息
Center for Human Genetics, University of Leuven, Belgium.
出版信息
Genes Chromosomes Cancer. 1996 Oct;17(2):136-9. doi: 10.1002/1098-2264(199610)17:2<136::aid-gcc2870170202>3.0.co;2-0.
Abstract
A new chromosome rearrangement, t(1;12)(p36;q13), is added to the cytogenetic changes found in renal oncocytomas. The breakpoint in 12q is cytogenetically different from those of the MAR region, and molecularly HMGIC located in 12q15 on the basis of 3' RACE experiments does not seem to be directly involved.
摘要
一种新的染色体重排，t(1;12)(p36;q13)，被添加到肾嗜酸细胞瘤中发现的细胞遗传学变化中。12q上的断点在细胞遗传学上与MAR区域的断点不同，并且基于3' RACE实验位于12q15的分子HMGIC似乎未直接参与其中。
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