Freitag L, Tekolf E, Steveling H, Donovan T J, Stamatis G
Ruhrlandklinik, Center for Pulmonary Medicine and Thoracic Surgery, Essen, Germany.
Chest. 1996 Nov;110(5):1155-60. doi: 10.1378/chest.110.5.1155.
Prognosis of inoperable or recurrent esophageal carcinoma is, at best, poor. Once an esophagotracheal fistula has developed, the overall condition of the patient declines rapidly. Aspiration pneumonia and severe coughing are common. The introduction of esophageal tubes does not always seal the fistula sufficiently and may compromise the airway causing stridor and dyspnea. In 30 patients (25 male, 5 female; age 23 to 74 years; mean, 56 years) with very large fistulas and airway problems, we inserted an airway stent (Dynamic) (n = 12) or an esophageal tube combined with a Dynamic airway stent (n = 18) with the aim of sealing the fistula and restoring patency of the airway and GI passage. The tracheobronchial Dynamic stent was chosen because its slightly concave, flexible posterior silicone membrane adapts ideally to the convex esophageal tube. The stents were well tolerated and significantly improved the quality of life. Of 30 patients, 16 could breathe and swallow unimpaired until shortly before their death. Moderate complaints persisted in five patients, dysphagia in eight patients, and dyspnea in one patient. Mean survival time in the double stent group was significantly greater (110 days) than in the airway stent-only group (24 days) or comparable groups in the literature treated with esophageal tubes only. We conclude that carefully selected patients can benefit from double stenting of esophagus and airways.
无法手术切除或复发的食管癌预后极差。一旦形成食管气管瘘,患者的整体状况会迅速恶化。吸入性肺炎和剧烈咳嗽很常见。插入食管管并不总能充分封闭瘘口,还可能危及气道,导致喘鸣和呼吸困难。在30例(25例男性,5例女性;年龄23至74岁,平均56岁)存在巨大瘘口和气道问题的患者中,我们插入了气道支架(Dynamic)(12例)或食管管联合Dynamic气道支架(18例),目的是封闭瘘口并恢复气道和胃肠道的通畅。选择气管支气管Dynamic支架是因为其略微凹陷、灵活的后部硅胶膜能理想地适配凸出的食管管。这些支架耐受性良好,显著改善了生活质量。30例患者中,16例在临终前不久仍能正常呼吸和吞咽。5例患者仍有中度不适,8例患者有吞咽困难,1例患者有呼吸困难。双支架组的平均生存时间(110天)显著长于仅使用气道支架组(24天)或文献中仅用食管管治疗的可比组。我们得出结论,经过精心挑选的患者可从食管和气道的双支架置入中获益。