• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

气道支架置入术和双支架置入术治疗恶性食管气管瘘

Management of malignant esophagotracheal fistulas with airway stenting and double stenting.

作者信息

Freitag L, Tekolf E, Steveling H, Donovan T J, Stamatis G

机构信息

Ruhrlandklinik, Center for Pulmonary Medicine and Thoracic Surgery, Essen, Germany.

出版信息

Chest. 1996 Nov;110(5):1155-60. doi: 10.1378/chest.110.5.1155.

DOI:10.1378/chest.110.5.1155
PMID:8915213
Abstract

Prognosis of inoperable or recurrent esophageal carcinoma is, at best, poor. Once an esophagotracheal fistula has developed, the overall condition of the patient declines rapidly. Aspiration pneumonia and severe coughing are common. The introduction of esophageal tubes does not always seal the fistula sufficiently and may compromise the airway causing stridor and dyspnea. In 30 patients (25 male, 5 female; age 23 to 74 years; mean, 56 years) with very large fistulas and airway problems, we inserted an airway stent (Dynamic) (n = 12) or an esophageal tube combined with a Dynamic airway stent (n = 18) with the aim of sealing the fistula and restoring patency of the airway and GI passage. The tracheobronchial Dynamic stent was chosen because its slightly concave, flexible posterior silicone membrane adapts ideally to the convex esophageal tube. The stents were well tolerated and significantly improved the quality of life. Of 30 patients, 16 could breathe and swallow unimpaired until shortly before their death. Moderate complaints persisted in five patients, dysphagia in eight patients, and dyspnea in one patient. Mean survival time in the double stent group was significantly greater (110 days) than in the airway stent-only group (24 days) or comparable groups in the literature treated with esophageal tubes only. We conclude that carefully selected patients can benefit from double stenting of esophagus and airways.

摘要

无法手术切除或复发的食管癌预后极差。一旦形成食管气管瘘,患者的整体状况会迅速恶化。吸入性肺炎和剧烈咳嗽很常见。插入食管管并不总能充分封闭瘘口,还可能危及气道,导致喘鸣和呼吸困难。在30例(25例男性,5例女性;年龄23至74岁,平均56岁)存在巨大瘘口和气道问题的患者中,我们插入了气道支架(Dynamic)(12例)或食管管联合Dynamic气道支架(18例),目的是封闭瘘口并恢复气道和胃肠道的通畅。选择气管支气管Dynamic支架是因为其略微凹陷、灵活的后部硅胶膜能理想地适配凸出的食管管。这些支架耐受性良好,显著改善了生活质量。30例患者中,16例在临终前不久仍能正常呼吸和吞咽。5例患者仍有中度不适,8例患者有吞咽困难,1例患者有呼吸困难。双支架组的平均生存时间(110天)显著长于仅使用气道支架组(24天)或文献中仅用食管管治疗的可比组。我们得出结论,经过精心挑选的患者可从食管和气道的双支架置入中获益。

相似文献

1
Management of malignant esophagotracheal fistulas with airway stenting and double stenting.气道支架置入术和双支架置入术治疗恶性食管气管瘘
Chest. 1996 Nov;110(5):1155-60. doi: 10.1378/chest.110.5.1155.
2
Dual Airway and Esophageal Stenting in Advanced Esophageal Cancer With Lesions Near Carina.隆突附近病变的晚期食管癌的双气道和食管支架置入术。
J Bronchology Interv Pulmonol. 2020 Oct;27(4):286-293. doi: 10.1097/LBR.0000000000000672.
3
Double stenting for esophageal and tracheobronchial stenoses.食管和气管支气管狭窄的双支架置入术
Ann Thorac Surg. 2000 Dec;70(6):1803-7. doi: 10.1016/s0003-4975(00)02042-7.
4
Double stenting with silicone and metallic stents for malignant airway stenosis.使用硅胶支架和金属支架联合治疗恶性气道狭窄。
Surg Today. 2017 Aug;47(8):1027-1035. doi: 10.1007/s00595-016-1466-6. Epub 2017 Jan 11.
5
Self-expanding plastic stents for inoperable malignant strictures of the cervical esophagus.用于不可手术的颈段食管恶性狭窄的自膨式塑料支架
Dis Esophagus. 2009;22(4):354-60. doi: 10.1111/j.1442-2050.2008.00931.x. Epub 2009 Jan 23.
6
Nonexpandable silicone esophageal stents for treatment of malignant tracheoesophageal fistulas: complications and radiographic appearances.用于治疗恶性气管食管瘘的不可扩张硅酮食管支架:并发症及影像学表现
Abdom Imaging. 1997 Jan-Feb;22(1):14-9. doi: 10.1007/s002619900131.
7
Alleviation of malignant dysphagia in inoperable lung cancer.无法手术的肺癌患者恶性吞咽困难的缓解。
Ann Palliat Med. 2023 Jul;12(4):738-747. doi: 10.21037/apm-22-1144. Epub 2023 Jul 11.
8
Gianturco-Z stents in the palliative treatment of malignant esophageal obstruction and esophagotracheal fistulas.Gianturco-Z支架在恶性食管梗阻和食管气管瘘姑息治疗中的应用
Endoscopy. 1995 Sep;27(7):495-500. doi: 10.1055/s-2007-1005754.
9
Utility of stent double palliation for esophageal cancer with airway involvement: the extremis of care.支架双重姑息治疗在气道受累食管癌中的应用:极限关怀。
Dis Esophagus. 2020 May 15;33(5). doi: 10.1093/dote/doz087.
10
Double stent for malignant combined esophago-airway lesions.用于恶性食管气道联合病变的双支架
Jpn J Thorac Cardiovasc Surg. 2002 Jan;50(1):1-5. doi: 10.1007/BF02913479.

引用本文的文献

1
Diagnostic and Therapeutic Challenges of Postoperative Bronchoesophageal Fistula Leading to Acute Respiratory Distress Syndrome.术后支气管食管瘘导致急性呼吸窘迫综合征的诊断与治疗挑战
Cureus. 2025 Mar 24;17(3):e81127. doi: 10.7759/cureus.81127. eCollection 2025 Mar.
2
Endoscopic management of tracheoesophageal fistulas: a narrative review.气管食管瘘的内镜治疗:一项叙述性综述
Mediastinum. 2025 Mar 6;9:4. doi: 10.21037/med-24-45. eCollection 2025.
3
Prognostic factors after therapeutic bronchoscopy for tracheo- or broncho-oesophageal fistulas: results from the EpiGETIF registry.
气管或支气管食管瘘治疗性支气管镜检查后的预后因素:来自EpiGETIF注册研究的结果
ERJ Open Res. 2025 Apr 7;11(2). doi: 10.1183/23120541.00435-2024. eCollection 2025 Mar.
4
Twenty years of anastomotic stenosis combined with tracheocolonic fistula after colon replacement esophagectomy: a case report.结肠代食管切除术后吻合口狭窄合并气管结肠瘘20年:一例报告
Front Oncol. 2024 Dec 12;14:1471603. doi: 10.3389/fonc.2024.1471603. eCollection 2024.
5
Efficacy of airway stenting and nasogastric tube insertion in airway-esophageal fistula patients with airways compromised by advanced malignancy.气道支架和鼻胃管插入术在气道恶性肿瘤晚期气道受损的气道-食管瘘患者中的疗效。
Clin Respir J. 2024 Feb;18(2):e13737. doi: 10.1111/crj.13737.
6
Management of aero-digestive fistulas in adults: the bronchoscopist's perspective.成人气道消化道瘘的管理:支气管镜医师的视角
Mediastinum. 2023 Jun 14;7:33. doi: 10.21037/med-22-38. eCollection 2023.
7
Forbearance with endobronchial stenting: cognisance before conviction.支气管内支架置入术的宽容:先认知,后定罪。
Eur Respir Rev. 2023 Mar 8;32(167). doi: 10.1183/16000617.0189-2022. Print 2023 Mar 31.
8
Use of airway stents to treat malignant tracheobronchial fistulas: Our six-year experience.使用气道支架治疗恶性气管支气管瘘:我们的六年经验。
Turk Gogus Kalp Damar Cerrahisi Derg. 2022 Apr 27;30(2):216-226. doi: 10.5606/tgkdc.dergisi.2022.20831. eCollection 2022 Apr.
9
Airway interventions for tracheobronchial involvement in esophageal carcinoma: a retrospective cohort outcome study and algorithmic approach.食管癌气管支气管受累的气道干预:一项回顾性队列结局研究及算法方法
J Thorac Dis. 2022 Jul;14(7):2565-2578. doi: 10.21037/jtd-22-138.
10
A rare cause of esophagopleural fistula due to intensity-modulated proton therapy: a case report and review of literature.因强度调制质子治疗导致食管胸膜瘘的罕见病因:病例报告及文献复习。
Clin J Gastroenterol. 2021 Aug;14(4):955-960. doi: 10.1007/s12328-021-01388-5. Epub 2021 Apr 27.