Strandburg R J, Marsh J T, Brown W S, Asarnow R F, Higa J, Harper R, Guthrie D
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA.
Biol Psychiatry. 1996 Nov 15;40(10):964-80. doi: 10.1016/0006-3223(95)00545-5.
Visual information processing in children with attention deficit hyperactivity disorder (ADHD) was studied using event-related potentials recorded during two versions of the Continuous Performance Task (CPT). ADHD children made more errors, and had longer reaction times than normal children on both the single- and dual-target CPT. Event-related potential waveforms were normal in the ADHD children with reference to early processing stages, i.e., contingent negative variation, P1-N1 laterality, and processing negativities, suggesting that ADHD children did not differ in their level of preparedness or their ability to mobilize resources for target identification and categorization. With respect to later processing, P3 amplitude was reduced in the ADHD group, whereas P3 latency was longer than normal. ADHD children had a diminished late frontal negative component, suggestive of reduced involvement in postdecisional processing.
采用在两种版本的连续作业任务(CPT)中记录的事件相关电位,对注意力缺陷多动障碍(ADHD)儿童的视觉信息处理进行了研究。在单目标和双目标CPT中,ADHD儿童比正常儿童犯的错误更多,反应时间更长。ADHD儿童的事件相关电位波形在早期处理阶段,即关联性负变、P1-N1偏侧性和处理负波方面是正常的,这表明ADHD儿童在准备水平或为目标识别和分类调动资源的能力方面没有差异。在后期处理方面,ADHD组的P3波幅降低,而P3潜伏期比正常儿童长。ADHD儿童的晚期额叶负成分减少,提示其在决策后处理中的参与度降低。