Moulaert A, Senders R, van Ertbruggen I, Huysmans H, Harinck E
Eur J Cardiol. 1977 Jun;5(4):321-5.
Prostaglandin type E1 has been administered on 4 different occasions in a newborn with a ductus-dependent complex congenital cyanotic heart disease. Dramatic improvement of the arterial oxygen concentration followed each prostaglandin infusion. Increased pulmonary circulation and widening of the ductus arteriosus were seen on angiographic examination. Transient flushing of the skin and mild pyrexia were the only complications noted. It is advised that prostaglandin type E1 be used in ductus-dependent heart diseases as an emergency therapy when indicated.
已对一名患有依赖动脉导管的复杂性先天性紫绀型心脏病的新生儿4次使用前列腺素E1。每次输注前列腺素后，动脉血氧浓度都有显著改善。血管造影检查显示肺循环增加和动脉导管增宽。仅观察到皮肤短暂潮红和轻度发热等并发症。建议在有指征时，将前列腺素E1用于依赖动脉导管的心脏病作为紧急治疗。
