Pérez-Santonja J J, Iradier M T, Sanz-Iglesias L, Serrano J M, Zato M A
Department of Ophthalmology, Jiménez-Díaz Foundation, Autonomous University of Madrid School of Medicine, Spain.
J Cataract Refract Surg. 1996 Oct;22(8):1017-22. doi: 10.1016/s0886-3350(96)80113-1.
To evaluate the long-term endothelial cell loss after implantation of Worst-Fechner and Baikoff ZB5M anterior chamber intraocular lenses.
Jiménez-Díaz Foundation and San Carlos University Hospital, Madrid, Spain.
Preoperative and serial postoperative specular microscopy was performed on 30 eyes that had a Worst-Fechner lens and on 28 eyes that had a Baikoff ZB5M lens to correct high myopia. A video specular microscope adapted to an image analysis system was used to analyze the endothelium for cell density. Follow-up was 24 months.
In the Worst-Fechner lens group, postoperative endothelial cell density was significantly lower than preoperative density at all times (P < .001). Endothelial cell loss was 7.26% at 3 months, 10.64% at 6 months, 13.00% at 12 months, and 17.60% at 24 months. In the Baikoff ZB5M lens group, postoperative cell density was also significantly lower than preoperative density at all times (P < .001). It was 7.50% at 3 months, 10.94% at 6 months, 12.33% at 12 months, and 12.30% at 24 months. Cell loss did not stabilize between 1 and 2 years after surgery in the Worst-Fechner group (P = .047). However, no additional cell loss was noted during this period in the Baikoff ZB5M group (P = .968). Endothelial cell densities in the two groups did not differ during the first year. However, 2 years after surgery, cell density in the Worst-Fechner group was significantly lower than it was in the ZB5M group (P = .048).
Endothelial cell loss during the first year was similar in eyes with Worst-Fechner and Baikoff ZB5M lenses; however, at 2 years after surgery, endothelial cell loss was higher in eyes with Worst-Fechner lenses than it was in eyes with Baikoff ZB5M lenses.
评估植入 Worst-Fechner 和 Baikoff ZB5M 前房型人工晶状体后内皮细胞的长期损失情况。
西班牙马德里的希门尼斯 - 迪亚斯基金会和圣卡洛斯大学医院。
对 30 只植入 Worst-Fechner 晶状体以及 28 只植入 Baikoff ZB5M 晶状体以矫正高度近视的眼睛进行术前和术后系列镜面反射显微镜检查。使用适配图像分析系统的视频镜面反射显微镜分析内皮细胞密度。随访时间为 24 个月。
在 Worst-Fechner 晶状体组，术后各时间点的内皮细胞密度均显著低于术前密度（P <.001）。3 个月时内皮细胞损失率为 7.26%，6 个月时为 10.64%，12 个月时为 13.00%，24 个月时为 17.60%。在 Baikoff ZB5M 晶状体组，术后各时间点的细胞密度也显著低于术前密度（P <.001）。3 个月时为 7.50%，6 个月时为 10.94%，12 个月时为 12.33%，24 个月时为 12.30%。Worst-Fechner 组术后 1 至 2 年细胞损失未稳定（P =.047）。然而，在此期间 Baikoff ZB5M 组未发现额外的细胞损失（P =.968）。两组第一年的内皮细胞密度无差异。然而，术后 2 年，Worst-Fechner 组的细胞密度显著低于 ZB5M 组（P =.048）。
植入 Worst-Fechner 和 Baikoff ZB5M 晶状体的眼睛在第一年的内皮细胞损失情况相似；然而，术后 2 年，植入 Worst-Fechner 晶状体的眼睛内皮细胞损失高于植入 Baikoff ZB5M 晶状体的眼睛。
