Schiano Lomoriello D, Lombardo M, Gualdi L, Iacobelli L, Tranchina L, Ducoli P, Serrao S
Fondazione G.B. Bietti IRCCS, Rome, Italy.
Open Ophthalmol J. 2013 Mar 22;7:20-3. doi: 10.2174/1874364101307010020. Print 2013.
To evaluate the position stability of a phakic intraocular lens (Cachet pIOL; Alcon, Laboratories, Inc., Fort Worth, TX) in the anterior chamber (AC) during a 6-months follow-up.
Thirty eyes of 16 subjects underwent a Cachet pIOL implantation for the correction of high myopia from -6.50 to -16.00 D with plano targeted refraction. The position stability of the Cachet pIOL was evaluated using an Anterior Segment-OCT (AS-OCT, Carl Zeiss AG, Oberkochen, Germany) at 1- and 6-months postoperatively. Three measurements have been taken into account: 1) the minimum distance between the anterior surface of the Cachet pIOL optic disk and the central corneal endothelium; 2) the minimum distance between the optic disk's edges of the pIOL and the endothelium; 3) the minimum distance between the posterior surface of the pIOL optic disk and the anterior surface of the crystalline lens. The endothelial cell density (ECD) was also recorded.
No statistically significant changes of the Cachet pIOL position in the AC were found during follow-up. The average changes were ≤0.1 mm between 1- and 6-months postoperatively (P>0.05). At the end of follow-up, The mean ECD loss was 0.7 % (from 2794 ± 337 cell/mm(2) to 2776 ± 388 cell/mm(2); P>0.05).
A high position stability of the Cachet pIOL in the anterior chamber was shown during a 6-months follow-up.
评估有晶状体眼人工晶状体（Cachet pIOL；爱尔康公司，美国得克萨斯州沃思堡）在前房（AC）内6个月随访期间的位置稳定性。
16名受试者的30只眼睛接受了Cachet pIOL植入手术，用于矫正-6.50至-16.00 D的高度近视，目标屈光为平光。在术后1个月和6个月时，使用眼前节光学相干断层扫描（AS-OCT，卡尔蔡司公司，德国奥伯科亨）评估Cachet pIOL的位置稳定性。考虑了三项测量指标：1）Cachet pIOL视盘前表面与中央角膜内皮之间的最小距离；2）pIOL视盘边缘与内皮之间的最小距离；3）pIOL视盘后表面与晶状体前表面之间的最小距离。同时记录内皮细胞密度（ECD）。
随访期间，未发现AC内Cachet pIOL位置有统计学意义的变化。术后1个月至6个月的平均变化≤0.1 mm（P>0.05）。随访结束时，平均ECD损失为0.7%（从2794±337个细胞/mm²降至2776±388个细胞/mm²；P>0.05）。
在6个月的随访期间，Cachet pIOL在前房内显示出较高的位置稳定性。
