Roztocil K, Prerovský I, Oliva I
Eur J Clin Pharmacol. 1977 Jul 19;11(6):435-8. doi: 10.1007/BF00562934.
The rate of capillary filtration in the lower limbs after hydroxyethylrutosides administered in various doses and by different routes was studied in patients with chronic venous insufficiency. Capillary filtration rate decreased immediately after intravenous and from 55 to 85 minutes after oral administration, depending on the dose. The slow-release tablets produced a definite falt in capillary filtration 240 minutes after administration.
在慢性静脉功能不全患者中,研究了不同剂量和不同给药途径给予羟乙基芦丁后下肢毛细血管滤过率。静脉给药后毛细血管滤过率立即下降,口服给药后55至85分钟下降,具体取决于剂量。缓释片给药后240分钟毛细血管滤过出现明显下降。