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产前可卡因/多种药物暴露:种族对结局的影响。

Prenatal cocaine/polydrug exposure: effect of race on outcome.

作者信息

Billman D O, Nemeth P B, Heimler R, Sasidharan P

机构信息

Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA.

出版信息

J Perinatol. 1996 Sep-Oct;16(5):366-9.

PMID:8915935
Abstract

OBJECTIVE

To determine the effect of prenatal exposure to cocaine on development.

METHODS

We tested 106 infants in the range of 4 to 30 months adjusted age with the Bayley Scales of Infant Development.

RESULTS

The 46 cocaine-exposed infants had similar mental scores to those of the 60 control infants. Among the 47 black infants, motor scores were 11.2 points higher in cocaine-exposed infants than in control infants (115.1 and 103.9, respectively, p = 0.023). Among the 59 white infants, motor scores were similar in cocaine-exposed infants (102.9) and control infants (100.6).

CONCLUSION

Genetic differences may account for this variation in motor development of cocaine-exposed infants.

摘要

目的

确定产前接触可卡因对发育的影响。

方法

我们用贝利婴儿发育量表对106名矫正年龄在4至30个月的婴儿进行了测试。

结果

46名接触可卡因的婴儿与60名对照婴儿的智力得分相似。在47名黑人婴儿中,接触可卡因的婴儿的运动得分比对照婴儿高11.2分(分别为115.1分和103.9分,p = 0.023)。在59名白人婴儿中,接触可卡因的婴儿(102.9分)和对照婴儿(100.6分)的运动得分相似。

结论

基因差异可能是接触可卡因婴儿运动发育存在这种差异的原因。

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