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难治性癫痫的微创手术方法

Minimally invasive surgical approach for intractable seizure.

作者信息

Patil A A, Andrews R, Torkelson R

机构信息

Division of Neurosurgery, University of Nebraska Medical Center, Omaha, USA.

出版信息

Stereotact Funct Neurosurg. 1995;65(1-4):86-9. doi: 10.1159/000098902.

DOI:10.1159/000098902
PMID:8916334
Abstract

Minimally invasive procedures (multiple subpial transection, topectomy and amygdalahippocampotomy) were used to treat 24 patients with intractable seizures. The seizure foci were in both hemispheres in 3 patients, all 4 lobes of a hemisphere in 1 patient, 3 lobes of a hemisphere in 5 patients, 2 lobes of a hemisphere in 11 patients and the temporal lobe alone in 4 patients. The longest follow-up is 41 months, with a median of 18 months. Sixteen patients have a follow-up of more than 1 years, with excellent results in 10 (66%) and good in the remaining 6 (38%). There were no permanent complications These results are encouraging, because the majority of the patients were poor candidates for surgery.

摘要

采用微创程序(多软膜下横切术、大脑皮质切除术和杏仁核海马切除术)治疗24例顽固性癫痫患者。癫痫病灶位于双侧半球的有3例,位于一个半球所有4个脑叶的有1例,位于一个半球3个脑叶的有5例,位于一个半球2个脑叶的有11例,仅位于颞叶的有4例。最长随访时间为41个月,中位数为18个月。16例患者随访超过1年,其中10例(66%)效果极佳,其余6例(38%)效果良好。无永久性并发症。这些结果令人鼓舞,因为大多数患者并非手术的理想人选。

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