Forsberg J G
Department of Anatomy, Biskopsgatan, Lund, Sweden.
Acta Obstet Gynecol Scand Suppl. 1996;163:3-10.
The author reviews basic facts on vaginal histology and ultrastructure with respect to passage of different substances and drugs through the epithelium. Particular interest is given to the action mechanism of topically applied intravaginal estrogen, its binding to receptors in different vaginal cell types, and possible local metabolic routes for estrogen. Differences in estrogen sensitivity between uterus and vagina are discussed as well as the background for the high sensitivity in the vagina.
作者回顾了关于不同物质和药物通过上皮细胞进入阴道的组织学和超微结构的基本事实。特别关注局部应用阴道雌激素的作用机制、其与不同阴道细胞类型中受体的结合以及雌激素可能的局部代谢途径。讨论了子宫和阴道对雌激素敏感性的差异以及阴道高敏感性的背景。
