Forsberg J G
Department of Anatomy, University of Lund, Sweden.
Maturitas. 1995 Dec;22 Suppl:S7-S15. doi: 10.1016/0378-5122(95)00957-4.
This paper reviews basic facts on vagina histology and ultrastructure with respect to passage of different substances and drugs through the epithelium. Particular interest is devoted to the action mechanism of topically-applied vaginal estrogen, its binding to receptors in different vaginal cell types, and possible local metabolic routes. Differences in estrogen sensitivity between uterus and vagina are discussed as well as the background for the high vaginal sensitivity.
本文综述了关于阴道组织学和超微结构的基本事实，涉及不同物质和药物通过上皮的情况。特别关注局部应用的阴道雌激素的作用机制、其与不同阴道细胞类型中受体的结合以及可能的局部代谢途径。还讨论了子宫和阴道之间雌激素敏感性的差异以及阴道高敏感性的背景。
