冠状动脉支架置入术后单用阿司匹林与阿司匹林加噻氯匹定的比较。
Comparison of aspirin alone versus aspirin plus ticlopidine after coronary artery stenting.
作者信息
Goods C M, al-Shaibi K F, Liu M W, Yadav J S, Mathur A, Jain S P, Dean L S, Iyer S S, Parks J M, Roubin G S
机构信息
Cardiovascular Division, University of Alabama at Birmingham 35294, USA.
出版信息
Am J Cardiol. 1996 Nov 1;78(9):1042-4. doi: 10.1016/s0002-9149(96)00532-2.
This prospective nonrandomized study was performed comparing aspirin alone (n = 46) versus aspirin and ticlopidine (p = 338) following native coronary artery stenting. There were significantly more stent thrombosis events in the aspirin-only group than in the aspirin and ticlopidine group (6.5% vs 0.9%, p = 0.02) and significantly more Q-wave myocardial infarctions and cardiac-related deaths in the aspirin-only group than in the aspirin and ticlopidine group (6.5% vs 0%, p = 0.002 and 4.4% vs 0.3% p = 0.02, respectively).
这项前瞻性非随机研究比较了单纯使用阿司匹林（n = 46）与阿司匹林和噻氯匹定联合使用（n = 338）在自体冠状动脉支架置入术后的情况。单纯使用阿司匹林组的支架血栓形成事件显著多于阿司匹林和噻氯匹定联合使用组（6.5% 对 0.9%，p = 0.02），且单纯使用阿司匹林组的Q波心肌梗死和心脏相关死亡显著多于阿司匹林和噻氯匹定联合使用组（分别为6.5% 对 0%，p = 0.002；4.4% 对 0.3%，p = 0.02）。
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