Moraga F, Monge C, Riquelme R, Llanos A J
Departamento de Medicina Experimental, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Comp Biochem Physiol A Physiol. 1996 Oct;115(2):111-5. doi: 10.1016/0300-9629(96)00016-3.
We compared blood oxygen affinity (P50) and hemoglobin concentration among fetal and maternal llamas and sheep, as respective examples of species native to high and low altitudes. P50, hemoglobin concentration and blood oxygen content were determined at sea level in 16 pregnant llamas, 6 pregnant sheep and their respective fetuses. P50 was similar in fetal llamas and sheep, but maternal llamas had higher blood oxygen affinity than maternal sheep. As a consequence, the P50 difference between mother and fetus was less in llamas than in sheep. Fetal llamas had higher hemoglobin concentrations than fetal sheep. In contrast, the maternal hemoglobin concentrations were similar. The blood oxygen content was higher in fetal and maternal llamas than in fetal and maternal sheep. We conclude that the llama, a species native to the altiplano, has a higher blood oxygen content than the sheep, as determined in the fetus by a high hemoglobin concentration and in the mother by a low P50.
我们比较了原产于高海拔和低海拔地区的骆驼和绵羊的胎儿及母体的血氧亲和力（P50）和血红蛋白浓度。在海平面条件下，对16只怀孕骆驼、6只怀孕绵羊及其各自的胎儿测定了P50、血红蛋白浓度和血氧含量。胎儿骆驼和绵羊的P50相似，但母体骆驼的血氧亲和力高于母体绵羊。因此，骆驼母体与胎儿之间的P50差异小于绵羊。胎儿骆驼的血红蛋白浓度高于胎儿绵羊。相比之下，母体血红蛋白浓度相似。胎儿和母体骆驼的血氧含量高于胎儿和母体绵羊。我们得出结论，原产于高原地区的骆驼，其血氧含量高于绵羊，在胎儿中表现为高血红蛋白浓度，在母体中表现为低P50。
