Yasui Y, Hasada K, Yang J G, Koiwai O
Laboratory of Biochemistry, Aichi Cancer Center Research Institute, Nagoya, Japan.
Gene. 1996 Oct 10;175(1-2):269-70. doi: 10.1016/0378-1119(96)00127-8.
We have isolated a genomic clone encoding human selenoprotein P including the putative promoter region. The gene spans 12 kb and consists of five exons with a start codon in the second exon. A typical TATA sequence, the recognition motifs for a GATA-binding factor and the liver-specific factors, HNF-1 and HNF-3, were detected upstream from the transcription start point.