The metabolism of the male antifertility agent 1-amino-3-chloropropan-2-ol in the rat.
作者信息
Jones A R, Murcott C, Milton D H, Flynn J
出版信息
Experientia. 1977 Jul 15;33(7):934-5. doi: 10.1007/BF01951290.
PMID:891780
Abstract
摘要
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本文引用的文献
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The rate of acetaldehyde metabolism in rabbits treated with antabuse (tetraethylthiuramdisulphide).用安塔布司（二硫化四乙秋兰姆）治疗的兔子中乙醛的代谢速率。
Acta Pharmacol Toxicol (Copenh). 1949 Oct;5(3):292-7. doi: 10.1111/j.1600-0773.1949.tb03394.x.
2
Male antifertility compounds: structure and activity relationships of U-5897, U-l5,646 and related substances.男性抗生育化合物：U-5897、U-15646及相关物质的结构与活性关系
J Reprod Fertil. 1970 Mar;21(2):263-6. doi: 10.1530/jrf.0.0210263.
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Post-testicular antifertility effects of epichlorohydrin and 2,3-xpoxypropanol.环氧氯丙烷和2,3-环氧丙醇的睾丸后抗生育作用。
Nature. 1970 Apr 4;226(5240):87. doi: 10.1038/226087a0.
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Is glycidol an active intermediate in the antifertility action of alpha-chlorhydrin in male rats?缩水甘油是否是α-氯醇对雄性大鼠抗生育作用中的活性中间体？
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Oral antifertility effects of halo propanediol derivatives in male rats.卤代丙二醇衍生物对雄性大鼠的口服抗生育作用。
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Effects of alpha-chlorohydrin and related compounds on the reproductive organs and fertility of the male rat.α-氯醇及相关化合物对雄性大鼠生殖器官和生育能力的影响。
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A new orally active male antifertility agent.一种新型口服活性男性抗生育剂。
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