α-氯醇的氧化代谢与精囊囊肿的化学诱导
The oxidative metabolism of alpha-chlorohydrin and the chemical induction of spermatocoeles.
作者信息
Jones A R, Murcott C
出版信息
Experientia. 1976 Sep 15;32(9):1135-6. doi: 10.1007/BF01927587.
PMID:971742
Abstract
alpha-Chlorohydrin (I) is oxidatively metabolized to beta-chlorolactic acid (III) and oxalic acid (IV). Deposition of calcium oxalate within the renal tubules is responsible for the toxic effects of alpha-chlorohydrin and a similar action on the epididymis or epididymal blood vessels could initiate the formation of spermatocoeles from this and other male antifertility agents.
摘要
α-氯醇（I）经氧化代谢生成β-氯乳酸（III）和草酸（IV）。肾小管内草酸钙的沉积是α-氯醇产生毒性作用的原因，而对附睾或附睾血管的类似作用可能会引发由此及其他男性抗生育药物导致的精子囊肿的形成。
Zotero 插件