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阿尔巴尼亚慢性肾衰竭的流行病学及肾脏服务提供情况

The epidemiology of chronic renal failure and provision of renal services in Albania.

作者信息

Khan I H, Thereska N, Barbullushi M, MacLeod A M

机构信息

Renal Unit Tirana, Albania.

出版信息

Nephrol Dial Transplant. 1996 Sep;11(9):1751-4.

PMID:8918617
Abstract

Tirana, the only dialysis facility in Albania (pop 4 million), has a stock of 12 patients and three haemodialysis machines. To determine the need for renal services in Albania we studied the incidence and outcome of patients with chronic renal failure (CRF) referred to the renal service in Tirana (pop 300 000) over 1 year. Case-notes of all patients with a serum creatinine concentration > or = 300 mumol/l during the study period (1992) were examined and outcome at 2 years recorded for each patient. In all, 84 patients (mean age 41.6 +/- 17.5 years, 56% male) were referred to nephrologists of whom 35 (42%) came from Tirana, giving an annual incidence of 116 per million pop. 77% were under 40 and had no co-morbid illness. Glomerulonephritis, the most common renal diagnosis, affected 26% patients. 22% patients (mean age 38 +/- 18.1) died within 2 years and only 5% received dialysis. The mean age of those who received dialysis was 29 +/- 8.3 compared with those who were not dialysed (42 +/- 18.0). The 59 patients (24 from Tirana i.e. 80 per million) who were alive with advanced CRF (creatinine > 500) had a mean creatine of 623 +/- 93 mumol/l and would be candidates for dialysis. Patients with progressive renal failure in Albania are regularly followed and treated with antihypertensives and dietary modification. The need for RRT, however, is not being met even for young patients with no co-morbidity.

摘要

地拉那是阿尔巴尼亚(人口400万)唯一的透析机构,有12名患者和三台血液透析机。为了确定阿尔巴尼亚对肾脏服务的需求,我们研究了在一年时间里转诊至地拉那(人口30万)肾脏服务机构的慢性肾衰竭(CRF)患者的发病率和转归情况。检查了研究期间(1992年)血清肌酐浓度≥300μmol/L的所有患者的病历,并记录了每位患者2年时的转归情况。共有84例患者(平均年龄41.6±17.5岁,56%为男性)转诊至肾病科医生处,其中35例(42%)来自地拉那,年发病率为每百万人口116例。77%的患者年龄在40岁以下,且无合并症。肾小球肾炎是最常见的肾脏诊断疾病,影响了26%的患者。22%的患者(平均年龄38±18.1岁)在2年内死亡,只有5%的患者接受了透析。接受透析患者的平均年龄为29±8.3岁,未接受透析患者的平均年龄为42±18.0岁。59例(24例来自地拉那,即每百万人口80例)患有晚期CRF(肌酐>500)且存活的患者,平均肌酐为623±93μmol/L,将成为透析候选者。阿尔巴尼亚进行性肾衰竭患者定期接受随访,并接受抗高血压药物治疗和饮食调整。然而,即使是没有合并症的年轻患者,对肾脏替代治疗(RRT)的需求也未得到满足。

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