Barman N N, Bhattacharyya R, Upadhyaya T N, Baishya G
Department of Microbiology, College of Veterinary Science, Assam Agricultural University, Khanapara, India.
Lung. 1996;174(2):127-31. doi: 10.1007/BF00177706.
Development of bronchus-associated lymphoid tissue (BALT) was studied in clinically healthy and diseased Assam local goats. Animals were sacrificed before term as well as at different postnatal periods to screen lung sections for the presence of BALT. In a retrospective study sections prepared from pneumonic lungs were examined for any alteration of BALT. No BALT-like structure was found in neonatal goats. Bronchial lymphoid structures appeared in half of the animals from 1 month of age onward. The frequency of the BALT/4.5 cm2 of lung section ranged from one to two in 1-month-old and three to six in 1-year-old goats. In pneumonic lungs BALT became hyperplastic, and the size was also increased. The incidence of BALT was increased in lungs with fibrotic pneumonia. The number of BALT/section was high (five to eight/4.5-cm2 area) in mesenchymal cell proliferation. The present study shows that BALT did not develop in prenatal periods. But in the presence of potent antigens lymphoid aggregates appeared in the bronchial lamina propria of normal and diseased lungs.
在临床健康和患病的阿萨姆本地山羊中研究了支气管相关淋巴组织（BALT）的发育情况。在足月前以及不同的出生后时期处死动物，以筛查肺切片中是否存在BALT。在一项回顾性研究中，检查了肺炎肺组织制备的切片中BALT的任何变化。新生山羊中未发现类似BALT的结构。从1月龄起，一半的动物出现了支气管淋巴结构。1月龄山羊每4.5平方厘米肺切片中BALT的数量为1至2个，1岁山羊为3至6个。在肺炎肺中，BALT增生，大小也增加。在纤维化肺炎的肺中，BALT的发生率增加。在间充质细胞增殖时，每切片中BALT的数量较高（每4.5平方厘米区域有5至8个）。本研究表明，BALT在产前未发育。但在存在强效抗原的情况下，正常和患病肺的支气管固有层中出现了淋巴聚集物。
