Yazdani I, Ahmad S, Channa A, Gayoor I
Department of Nephrology, Liaquat National Hospital, Karachi.
J Pak Med Assoc. 1995 Dec;45(12):320-3.
The study was undertaken to observe the co-relation between microangiopathic changes in diabetic retinopathy and microvascular changes in diabetic nephropathy. Included in the study were 64 patients with chronic renal failure who were on maintenance dialysis, 40 had hypertension alone, 21 hypertension and diabetes and 3 had diabetes alone. On examination of retina, of 40 hypertensive patients, 14 had positive findings, while in the hypertensive and diabetic group, 20 patients out of 21, had positive findings. Nine patients in the hypertensive group had delayed choroidal filling on fluorescein angiography which was not very accurately reflected on Funduscopy. In the diabetic and hypertensive group, 13 patients having proteinuria of more than 1 gm, also had exudates and haemorrhages in the fundus. It was concluded that a correlation exists between the arterial changes in the fundus of the eye and the glomeruli of the kidney.
本研究旨在观察糖尿病视网膜病变的微血管病变与糖尿病肾病的微血管变化之间的相关性。研究纳入了64例接受维持性透析的慢性肾衰竭患者,其中40例仅患有高血压,21例患有高血压和糖尿病,3例仅患有糖尿病。在眼底检查中,40例高血压患者中有14例有阳性发现,而在高血压合并糖尿病组中,21例患者中有20例有阳性发现。高血压组中有9例患者在荧光素血管造影中脉络膜充盈延迟,这在眼底镜检查中并未得到非常准确的反映。在糖尿病合并高血压组中,13例蛋白尿超过1克的患者眼底也有渗出物和出血。得出的结论是,眼底动脉变化与肾脏肾小球变化之间存在相关性。