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[节律性皮层刺激参数在运动神经元突触激活中的作用]

[Role of parameters of rhythmic cortical stimulation in synaptic activation of motor neurons].

作者信息

Blagodatove E T, Evdokimov S A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1977 Jul;63(7):929-37.

PMID:892096
Abstract

Postsynaptic potentials (PSPs) evoked by stimulation of contralateral motor cortex with trains of square stimuli were recorded intracellularly in cat lumbar motoneurons. The influence of number of stimuli in a train and of interval between them upon amplitude, duration and latency of PSPs, was analysed. Rise of stimuli frequency in a train of constant duration (i.e. rise of number of stimuli accompanied by shortening of intervals) produced a snyaptic effect that was much more pronounced than in cases of shortening of intervals between equal number of stimuli (i.e. reduction of a train) or in cases of increase of number of stimuli with equal intervals (elongation of a train). Possible neuronal mechanisms of the leading role of train frequency in supraspinal activation of motoneurons are discussed.

摘要

用方形刺激串刺激对侧运动皮层所诱发的突触后电位(PSP),在猫的腰段运动神经元中进行了细胞内记录。分析了刺激串中的刺激数量及其之间的间隔对PSP的幅度、持续时间和潜伏期的影响。在恒定持续时间的刺激串中增加刺激频率(即刺激数量增加伴随间隔缩短)所产生的突触效应,比在相同数量刺激之间缩短间隔(即刺激串缩短)或在等间隔增加刺激数量(刺激串延长)的情况下更为明显。文中讨论了刺激串频率在脊髓上运动神经元激活中起主导作用的可能神经元机制。

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