Laake K, Sverre J M
Department of Geriatric Medicine, Ullevaal Hospital, Oslo, Norway.
Age Ageing. 1996 Sep;25(5):343-8. doi: 10.1093/ageing/25.5.343.
Seasonal fluctuations in mortality are associated with age, outdoor temperature, and influenza. The relative excess winter mortality is approximately twice as high in the UK compared with the Scandinavian countries. Using data from Norway and England plus Wales, this study compares the effect of age, temperature and influenza on winter excess mortality in the two countries. Bivariate analyses showed that the excess winter mortality (December-March) in England and Wales was nearly twice as high in old as in middle-aged people, and also markedly higher than in Norway, while the association between excess winter deaths and influenza was of a similar magnitude. In the British data only, a marked and statistically significant negative relationship existed between outdoor temperature and excess winter mortality, corresponding to an increase of approximately 3,500 deaths in England and Wales (approximately 2/10,000 in the population aged 45 years and over) per 1 degree C reduction in winter temperature, after adjustment for age and influenza. Using data from 20 Western European countries, a highly significant positive correlation (R = 0.71, p < 0.001) was found between total mortality rates for the elderly (65 years and over) and relative excess winter mortality.
死亡率的季节性波动与年龄、室外温度及流感有关。与斯堪的纳维亚国家相比,英国冬季相对超额死亡率约为其两倍。本研究利用挪威、英格兰及威尔士的数据,比较了年龄、温度及流感对两国冬季超额死亡率的影响。双变量分析显示,英格兰和威尔士冬季(12月至次年3月)超额死亡率在老年人中几乎是中年人的两倍,且明显高于挪威,而超额死亡与流感之间的关联程度相似。仅在英国数据中,室外温度与冬季超额死亡率之间存在显著且具有统计学意义的负相关关系,调整年龄和流感因素后,英格兰和威尔士冬季温度每降低1摄氏度,超额死亡人数约增加3500人(45岁及以上人群中约为万分之二)。利用20个西欧国家的数据,发现老年人(65岁及以上)的总死亡率与冬季相对超额死亡率之间存在高度显著的正相关(R = 0.71,p < 0.001)。