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肛肠疾病

Anorectal disorders.

作者信息

Janicke D M, Pundt M R

机构信息

Department of Emergency Medicine, State University of New York at Buffalo, Millard Fillmore Hospitals, USA.

出版信息

Emerg Med Clin North Am. 1996 Nov;14(4):757-88. doi: 10.1016/s0733-8627(05)70278-9.

Abstract

Anorectal disorders are commonly encountered in the practice of emergency medicine. Most can be diagnosed and treated in the emergency department setting. Almost all anorectal disorders once diagnosed and treated in the emergency department need appropriate follow-up to ensure adequacy of treatment, for further possible diagnostic procedures (e.g., endoscopy, biopsy), or for definitive treatment. Hemorrhoids are the most prevalent anorectal disorder and are the most common cause of hematochezia. Treatment is dependent on the degree of hemorrhoid prolapse and symptoms. Most cases can be treated by conservative medical treatment (e.g., dietary changes, sitz baths) or nonsurgical procedures (e.g., rubber band liagation, infrared coagulation). Surgical excision of symptomatic thrombosed external hemorrhoids is indicated if within 48 to 72 hours of pain onset. Anal fissures are one of the most common causes of anorectal pain. They are most frequently idiopathic, and most are located in the posterior midline of the anal canal. Most anal fissures are adequately treated by a medical approach using sitz baths, stool softeners, and analgesics. If the anal fissure becomes chronic and is not responsive to medical therapy, a lateral sphincterotomy of the internal anal sphincter is the surgical procedure of choice. Pharmacologic treatment (botulinum toxin or nitroglycerin ointment) to decrease internal anal sphincter tone has shown promise in the treatment of anal fissure. Anorectal abscesses are categorized into four types: perianal, ischiorectal, intersphincteric, and supralevator. Most are idiopathic and contain mixed aerobic-anaerobic pathogens. Fistula formation varies from 25% to 50% and is much more common with gut-derived organisms (e.g., E. coli, B. fragilis). Definitive treatment for an anorectal abscess is timely surgical incision and drainage to prevent more serious complications (e.g., serious infection, extension of the abscess). Anal carcinomas are infrequent, the majority of them being squamous cell or epidermoid carcinomas. The emergency physician must maintain a high index of suspicion and obtain a biopsy of suspicious lesions in order not to miss the diagnosis of a cancer. The most common presenting complaint of anal tumors is rectal bleeding. Combination chemotherapy and radiotherapy have shown promising results in the treatment of anal canal tumors. Bacterial, viral, and protozoal infections can be transmitted to the anorectum via anoreceptive intercourse. Such infections must be considered when a patient presents with rectal pain or discharge, tenesmus, or rectal or perineal ulcers. Proctosigmoidoscopy and rectal cultures may be necessary to determine the cause. Potential rectal complications of HIV infection include infectious diarrhea, acyclovir-resistant strains of HSV2, Kaposi's sarcoma, lymphoma, and squamous cell carcinoma. Rectal injuries may result from penetrating or blunt trauma, iatrogenic injuries, or foreign bodies. Rectal injury should be suspected when a patient presents with low abdominal, pelvic, or perineal pain or blood per rectum after sustaining trauma or undergoing an endoscopic or surgical procedure. Tetanus prophylaxis, intravenous antibiotics, and surgical intervention are indicated in all but superficial rectal tears.

摘要

肛肠疾病在急诊医学实践中很常见。大多数肛肠疾病可以在急诊科进行诊断和治疗。几乎所有在急诊科确诊并治疗的肛肠疾病都需要适当的随访,以确保治疗的充分性、进行进一步可能的诊断程序(如内镜检查、活检)或进行确定性治疗。痔疮是最常见的肛肠疾病,也是便血最常见的原因。治疗取决于痔疮脱垂的程度和症状。大多数病例可以通过保守药物治疗(如饮食改变、坐浴)或非手术程序(如橡皮圈套扎、红外线凝固)进行治疗。如果症状性血栓性外痔在疼痛发作后48至72小时内,需进行手术切除。肛裂是肛肠疼痛最常见的原因之一。它们大多是特发性的,大多数位于肛管后中线。大多数肛裂通过使用坐浴、大便软化剂和镇痛药的药物治疗方法可得到充分治疗。如果肛裂变为慢性且对药物治疗无反应,选择性的手术是内括约肌侧切术。降低内括约肌张力的药物治疗(肉毒杆菌毒素或硝酸甘油软膏)在肛裂治疗中已显示出前景。肛管直肠周围脓肿分为四种类型:肛周、坐骨直肠窝、括约肌间和骨盆直肠间隙。大多数是特发性的,含有需氧菌和厌氧菌混合病原体。肛瘘形成率在25%至50%之间,肠道来源的微生物(如大肠杆菌、脆弱拟杆菌)更易发生。肛管直肠周围脓肿的确定性治疗是及时进行手术切开引流,以防止更严重的并发症(如严重感染、脓肿扩散)。肛管癌不常见,大多数为鳞状细胞癌或表皮样癌。急诊医生必须保持高度的怀疑指数,并对可疑病变进行活检,以免漏诊癌症。肛管肿瘤最常见的主诉是直肠出血。联合化疗和放疗在肛管肿瘤治疗中已显示出有希望的结果。细菌、病毒和原生动物感染可通过肛交传播至肛管直肠。当患者出现直肠疼痛或分泌物、里急后重、或直肠或会阴溃疡时,必须考虑此类感染。可能需要进行直肠乙状结肠镜检查和直肠培养以确定病因。HIV感染的潜在直肠并发症包括感染性腹泻、对阿昔洛韦耐药的HSV2毒株、卡波西肉瘤、淋巴瘤和鳞状细胞癌。直肠损伤可能由穿透性或钝性创伤、医源性损伤或异物引起。当患者在遭受创伤或接受内镜或外科手术后出现下腹部、盆腔或会阴疼痛或直肠出血时,应怀疑直肠损伤。除了表浅的直肠撕裂外,所有患者均需进行破伤风预防、静脉注射抗生素和手术干预。

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