真性红细胞增多症增殖期髓外造血所致脊髓压迫症

Spinal cord compression due to extramedullary hematopoiesis in the proliferative phase of polycythemia vera.

作者信息

de Morais J C, Spector N, Lavrado F P, Nobre L F, de Mattos J P, Pulcheri W, Nucci M, Novis S, de Oliveira H P

机构信息

University Hospital, Federal University of Rio de Janeiro, Brazil.

出版信息

Acta Haematol. 1996;96(4):242-4. doi: 10.1159/000203792.

DOI:10.1159/000203792

PMID:8922492

Abstract

Extramedullary hematopoiesis is a common accompaniment of a variety of hematologic diseases such as hereditary spherocytosis, thalassemia and myelofibrosis. The association of extramedullary hematopoiesis with polycythemia vera in the proliferative phase is much less usual. We report a patient who presented with paraplegia due to spinal cord compression; clinical investigation revealed a paravertebral hematopoietic tumor, and the diagnosis of polycythemia vera was then established.

摘要

髓外造血是多种血液系统疾病的常见伴随表现，如遗传性球形红细胞增多症、地中海贫血和骨髓纤维化。在增殖期，髓外造血与真性红细胞增多症的关联则较为少见。我们报告一例因脊髓受压导致截瘫的患者；临床检查发现椎旁造血肿瘤，随后确诊为真性红细胞增多症。