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Dimorphic expression of calbindin-D28K in the medial basal hypothalamus from perinatal male and female rats.

作者信息

Lephart E D

机构信息

Department of Zoology, Brigham Young University, Provo, UT 84602, USA.

出版信息

Brain Res Dev Brain Res. 1996 Oct 23;96(1-2):281-4. doi: 10.1016/0165-3806(96)00100-9.

Abstract

Developmental expression of calbindin-D28K (CALB) in the medial basal hypothalamic (MBH) and amygdaloid (AMY) regions was examined by Western analysis. Males displayed significantly higher CALB levels compared to females in the MBH (but not the AMY) from gestational day 17 through postnatal day 1. These data imply that androgens or other hormonal factors regulate MBH CALB expression which in turn may modulate sexually dimorphic brain structures by preventing cell loss during neuronal development.

摘要

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