Aldren C P, FitzGerald J E, Kelly P, Birchall J P, Murray A
Department of Otolaryngology, Freeman Hospital, Newcastle upon Tyne.
Br J Audiol. 1996 Oct;30(5):325-31. doi: 10.3109/03005369609076780.
A new method of measuring the vestibulo-ocular reflex (VOR) during active head movements is presented. Subjects sat and attempted to maintain their gaze upon a fixed point whilst turning their heads from side to side in response to an auditory cue, to attain frequencies of head rotation that increased from 1 Hz to 4 Hz during a 24 s period. Head movements were monitored by a small magnetic field detector worn on the subject's forehead and positioned a set distance from a magnetic field transmitter coil. Eye movements were monitored using the corneo-retinal potential. Gain (eye angle/head angle) and phase difference (eye phase-head phase) were calculated to define the VOR. Three repeat measurements were made on 20 normal subjects. Gain decreased significantly (P < 0.0001) with increasing frequency whilst the phase difference remained unchanged. The 95% prediction intervals were narrow for both gain (+/- 0.28) and phase (+/- 11 degrees). These data, together with the speed and ease of performance of the test, suggest that the test can provide valuable information on the performance of the vestibular system.
本文介绍了一种在头部主动运动期间测量前庭眼反射(VOR)的新方法。受试者坐着,在听到听觉提示后,尝试在左右转头的同时将目光保持在一个固定点上,在24秒内达到从1赫兹增加到4赫兹的头部旋转频率。头部运动由佩戴在受试者前额的小型磁场探测器监测,该探测器与磁场发射线圈保持设定距离。使用角膜视网膜电位监测眼球运动。计算增益(眼角度/头角度)和相位差(眼相位-头相位)来定义VOR。对20名正常受试者进行了三次重复测量。随着频率增加,增益显著降低(P < 0.0001),而相位差保持不变。增益(±0.28)和相位(±11度)的95%预测区间都很窄。这些数据,连同测试的速度和执行的简便性,表明该测试可以提供有关前庭系统性能的有价值信息。