UDP-N-乙酰半乳糖胺：多肽N-乙酰半乳糖胺基转移酶家族控制粘蛋白型O-连接糖基化的起始。 - Suppr

Suppr

超能文献

A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation.

作者信息

Clausen H, Bennett E P

机构信息

Department of Oral Diagnostics, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Denmark.

出版信息

Glycobiology. 1996 Sep;6(6):635-46. doi: 10.1093/glycob/6.6.635.

DOI:10.1093/glycob/6.6.635

PMID:8922959

Abstract

摘要

相似文献

A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation.UDP-N-乙酰半乳糖胺：多肽N-乙酰半乳糖胺基转移酶家族控制粘蛋白型O-连接糖基化的起始。

Glycobiology. 1996 Sep;6(6):635-46. doi: 10.1093/glycob/6.6.635.

Cloning, expression and properties of porcine trachea UDP-galnac: polypeptide N-acetylgalactosaminyl transferase.猪气管UDP-N-乙酰半乳糖胺：多肽N-乙酰半乳糖胺基转移酶的克隆、表达及特性

Mol Cell Biochem. 2004 Nov;266(1-2):117-26. doi: 10.1023/b:mcbi.0000049148.73497.01.

Role of peptide sequence and neighboring residue glycosylation on the substrate specificity of the uridine 5'-diphosphate-alpha-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyl transferases T1 and T2: kinetic modeling of the porcine and canine submaxillary gland mucin tandem repeats.肽序列和相邻残基糖基化对尿苷5'-二磷酸-α-N-乙酰半乳糖胺：多肽N-乙酰半乳糖胺基转移酶T1和T2底物特异性的作用：猪和犬下颌下腺粘蛋白串联重复序列的动力学建模

Biochemistry. 2004 Aug 3;43(30):9888-900. doi: 10.1021/bi049178e.

Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.黏蛋白型 O-糖基化的调控：多肽 N-乙酰半乳糖胺转移酶基因家族的分类。

Glycobiology. 2012 Jun;22(6):736-56. doi: 10.1093/glycob/cwr182. Epub 2011 Dec 18.

The participation of ribosome-UDP-GalNAc complex in the initiation of protein glycosylation in vitro.核糖体 - UDP - N - 乙酰半乳糖胺复合物在体外蛋白质糖基化起始过程中的参与。

Acta Biochim Pol. 2000;47(2):421-6.

Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N-acetylgalactosaminyltransferase that complements other GalNAc-transferases in complete O-glycosylation of the MUC1 tandem repeat.一种人源UDP-N-乙酰-α-D-半乳糖胺：多肽N-乙酰半乳糖胺基转移酶的克隆，该酶在MUC1串联重复序列的完全O-糖基化过程中可补充其他N-乙酰半乳糖胺转移酶的功能。

J Biol Chem. 1998 Nov 13;273(46):30472-81. doi: 10.1074/jbc.273.46.30472.

Mucin core O-glycosylation is modulated by neighboring residue glycosylation status. Kinetic modeling of the site-specific glycosylation of the apo-porcine submaxillary mucin tandem repeat by UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases T1 and T2.粘蛋白核心O-糖基化受相邻残基糖基化状态的调节。UDP-GalNAc：多肽N-乙酰半乳糖胺基转移酶T1和T2对载脂蛋白猪颌下粘蛋白串联重复序列进行位点特异性糖基化的动力学建模。

J Biol Chem. 2002 Dec 20;277(51):49850-62. doi: 10.1074/jbc.M205851200. Epub 2002 Oct 22.

O-glycosylation in Toxoplasma gondii: identification and analysis of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases.弓形虫中的O-糖基化：UDP-N-乙酰半乳糖胺：多肽N-乙酰半乳糖胺基转移酶家族的鉴定与分析

Int J Parasitol. 2004 Mar 9;34(3):309-22. doi: 10.1016/j.ijpara.2003.11.016.

An efficient approach for the characterization of mucin-type glycopeptides: the effect of O-glycosylation on the conformation of synthetic mucin peptides.一种用于鉴定黏蛋白型糖肽的有效方法：O-糖基化对合成黏蛋白肽构象的影响。

Chemistry. 2011 Feb 18;17(8):2393-404. doi: 10.1002/chem.201002754. Epub 2011 Jan 24.

Brain-specific expression of a novel human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T9).一种新型人类UDP-N-乙酰半乳糖胺：多肽N-乙酰半乳糖胺基转移酶（GalNAc-T9）的脑特异性表达。

Biochim Biophys Acta. 2000 Sep 7;1493(1-2):264-8. doi: 10.1016/s0167-4781(00)00180-9.

引用本文的文献

Glycosylation in Cancer.癌症中的糖基化

Handb Exp Pharmacol. 2025;288:243-293. doi: 10.1007/164_2025_751.

Benefits and Pitfalls of a Glycosylation Inhibitor Tunicamycin in the Therapeutic Implication of Cancers.糖基化抑制剂衣霉素在癌症治疗中的益处与风险

Cells. 2024 Feb 25;13(5):395. doi: 10.3390/cells13050395.

Stromal-epithelial interaction induces in prostate carcinoma cells.基质-上皮相互作用在前列腺癌细胞中诱导产生。

Front Oncol. 2023 Aug 21;13:1212585. doi: 10.3389/fonc.2023.1212585. eCollection 2023.

ST6GALNAC4 promotes hepatocellular carcinogenesis by inducing abnormal glycosylation.ST6GALNAC4 通过诱导异常糖基化促进肝细胞癌发生。

J Transl Med. 2023 Jun 29;21(1):420. doi: 10.1186/s12967-023-04191-7.

Clinical relevance of biomarkers, new therapeutic approaches, and role of post-translational modifications in the pathogenesis of Alzheimer's disease.生物标志物的临床相关性、新的治疗方法以及翻译后修饰在阿尔茨海默病发病机制中的作用。

Front Aging Neurosci. 2022 Sep 7;14:977411. doi: 10.3389/fnagi.2022.977411. eCollection 2022.

Oviducal gland transcriptomics of through physiological stages and the negative effects of temperature on fertilization.通过生理阶段和温度对受精的负面影响研究的输卵管转录组学。

PeerJ. 2022 Mar 30;10:e12895. doi: 10.7717/peerj.12895. eCollection 2022.

An efficient system for bioconjugation based on a widely applicable engineered O-glycosylation tag.基于广泛适用的工程化 O-糖基化标签的生物偶联高效体系。

MAbs. 2021 Jan-Dec;13(1):1992068. doi: 10.1080/19420862.2021.1992068.

Human Lectins, Their Carbohydrate Affinities and Where to Find Them.人源凝集素、它们的碳水化合物亲和性以及它们的来源。

Biomolecules. 2021 Jan 29;11(2):188. doi: 10.3390/biom11020188.

Potential of Anti-MUC1 Antibodies as a Targeted Therapy for Gastrointestinal Cancers.抗MUC1抗体作为胃肠道癌症靶向治疗的潜力

Vaccines (Basel). 2020 Nov 5;8(4):659. doi: 10.3390/vaccines8040659.

GALNT6 promotes breast cancer metastasis by increasing mucin-type O-glycosylation of α2M.GALNT6 通过增加 α2M 的粘蛋白型 O-糖基化促进乳腺癌转移。

Aging (Albany NY). 2020 Jun 18;12(12):11794-11811. doi: 10.18632/aging.103349.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验