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[头颈部手术中的局部麻醉]

[Local anesthesia in operations of the head-neck area].

作者信息

Grevers G, Ledderose H

机构信息

Hals-Nasen-Ohrenklinik der Ludwig-Maximilians-Universität München.

出版信息

Laryngorhinootologie. 1996 Jul;75(7):433-6. doi: 10.1055/s-2007-997609.

Abstract

BACKGROUND

Many operations in the head and neck area can be performed under local anesthesia. However, the use of local anesthesia does not automatically reduce the risk for the patient undergoing surgery.

RESULTS

In the present paper, the authors discuss local anesthetics used in surgical procedures in the head and neck region. Aminoesters are currently the most commonly used local anesthetics. Local anesthetics vary with respect to the onset and duration of the local anesthetic effect. The choice of local anesthetic depends on the estimated duration of the surgical procedure. Possible side effects of these substances may affect the central nervous as well as the cardiovascular system. Certain changes in serum electrolytes (i.e., hyperkalemia) as well as hypoxia and hypercapnia significantly increase the cardiotoxic potential of local anesthetics. Different vasoconstrictor agents are used in addition to local anesthetics to prolong the duration of the local anesthetic effect and to provide the surgeon with a nearly bloodless field. The two groups of vasoconstrictors used in these days are catecholamines (epinephrine) and vasopressin analogs. Systemic side effects of catecholamines include cardiovascular reaction, mainly in patients with typical risk factors (i.e., coronary heart disease, high blood pressure, or chronic heart failure). Vasopressin analogs produce fewer side effects than epinephrine. Even so, an overdose of these vasoconstrictors might still result in severe cardiac complications. The recommended maximum doses of these drugs should be strictly observed.

CONCLUSIONS

For several reasons, local anesthesia has become popular for a variety of surgical procedures in the head and neck in recent years. Even though the use of local anesthetics and vasoconstrictors in head and neck procedures has its advantages for both the patient and the surgeon, the limitations for the use of these drugs must always be taken into consideration.

摘要

背景

头颈部区域的许多手术都可以在局部麻醉下进行。然而,使用局部麻醉并不会自动降低手术患者的风险。

结果

在本文中,作者讨论了头颈部手术中使用的局部麻醉剂。氨基酯类目前是最常用的局部麻醉剂。局部麻醉剂在局部麻醉效果的起效时间和持续时间方面各不相同。局部麻醉剂的选择取决于手术预计的持续时间。这些物质可能的副作用会影响中枢神经系统以及心血管系统。血清电解质的某些变化(即高钾血症)以及缺氧和高碳酸血症会显著增加局部麻醉剂的心脏毒性潜力。除局部麻醉剂外,还使用不同的血管收缩剂来延长局部麻醉效果的持续时间,并为外科医生提供几乎无血的手术视野。目前使用的两类血管收缩剂是儿茶酚胺(肾上腺素)和血管加压素类似物。儿茶酚胺的全身副作用包括心血管反应,主要发生在具有典型风险因素(即冠心病、高血压或慢性心力衰竭)的患者中。血管加压素类似物产生的副作用比肾上腺素少。即便如此,这些血管收缩剂过量仍可能导致严重的心脏并发症。应严格遵守这些药物的推荐最大剂量。

结论

由于多种原因,近年来局部麻醉在头颈部的各种手术中变得很普遍。尽管在头颈部手术中使用局部麻醉剂和血管收缩剂对患者和外科医生都有其优点,但必须始终考虑这些药物使用的局限性。

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