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[呼吸系统对空气污染物反应的变异性。克拉科夫儿童的流行病学研究]

[Variability of respiratory system reactions to air pollutants. Epidemiologic study of children in Cracow].

作者信息

Jedrychowski W, Flak E, Mróz E

机构信息

Katedry Epidemiologiii i Medycyny Zapobiegawczej, Collegium Medicum Uj.

出版信息

Pneumonol Alergol Pol. 1996;64(5-6):267-75.

PMID:8924877
Abstract

The main purpose of the study was to corroborate the hypothesis that the history of allergic skin reactions is the marker of individual susceptibility of respiratory tract to air pollutants in children. The study has been carried out in two contrast areas of the city regarding the air pollution level. In the dirty area the annual daily mean concentrations of particulate matter was 51.5-74.5 micrograms/m3 and sulfur dioxide 58.4-73.8 micrograms/m3; in the cleaner part of the city the corresponding concentrations were 31.7 and 36.1 micrograms/m3. The medical examination of 171 children covered standardized interviews with mothers and spirometric measurements. The results obtained showed that despite the marked decline in air pollution level, the current level of common air pollutants in the city is hazardous to the health of inhabitants. The children with history of allergic skin reactions have been affected much stronger by the higher level of air pollutants than other children. Beside the higher frequency of chronic cough or phlegm, wheezing or shortness of breath, they had significantly poorer lung function measured by FEVI/FVC index.

摘要

该研究的主要目的是证实这一假设

过敏性皮肤反应史是儿童呼吸道对空气污染物个体易感性的标志。该研究在城市中空气污染水平不同的两个对比区域进行。在污染严重的区域,颗粒物的年日均浓度为51.5 - 74.5微克/立方米,二氧化硫为58.4 - 73.8微克/立方米;在城市较清洁的区域,相应浓度分别为31.7和36.1微克/立方米。对171名儿童的医学检查包括与母亲的标准化访谈和肺活量测定。所得结果表明,尽管空气污染水平显著下降,但城市中常见空气污染物的当前水平对居民健康仍有危害。有过敏性皮肤反应史的儿童比其他儿童受较高水平空气污染物的影响更大。除了慢性咳嗽或咳痰、喘息或呼吸急促的发生率较高外,他们通过FEVI/FVC指数测量的肺功能明显更差。

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