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[Genetic risks associated with intracytoplasmic sperm injection].

作者信息

Plachot M

机构信息

Laboratoire de Recherche en Fécondation in Vitro et Biologie de la Reproduction, Hôpital Necker, Paris.

出版信息

Contracept Fertil Sex. 1996 Jul-Aug;24(7-8):577-80.

PMID:8924959
Abstract

Preliminary data available for ICSI demonstrate an increased incidence of chromosome abnormalities in infertile men, their spermatozoa and in the preimplantation embryos obtained after microinjection. The injection itself may not result in a significant increase in damage to the meiotic spindle provided care is taken to orient the polar body away to the site of injection. It is therefore of paramount importance to continue all investigations on larger series to properly evaluate the safety of the ICSI procedure.

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