Pelevina I I, Gotlib V Ia, Kudriashova O V, Serebrianyĭ A M, Afanas'ev G G
Radiats Biol Radioecol. 1996 Jul-Aug;36(4):546-60.
The results of series investigations of late effects after Chernobyl accident are discussed. Genomic instability induced by chronic irradiation of cultural cells in Chernobyl zone and in laboratory conditions have been studied. It was shown that low level prolonged irradiation result in increase of frequency of cells with micronuclei, giant cells, enhancement of radiosensitivity in descendents of early irradiated cells. Chronic low doses irradiation doesn't induce the adaptive response. Comparative investigation of adaptive response in blood lymphocytes of people (adults and children) living in Moscow and in regions polluted with radionuclides (5-40 ci/km2) after Chernobyl disaster have been conducted. In population from contaminated areas the frequency of individuals with definite adaptive response is decreased and there are individuals with increasing radiosensitivity after irradiation in conditioned dose. Chronic irradiation during living on contaminated areas don't induce the adaptive response.
本文讨论了切尔诺贝利事故后期影响的系列调查结果。研究了切尔诺贝利地区及实验室条件下培养细胞长期受照射所诱导的基因组不稳定性。结果表明，低水平长期照射会导致含微核细胞、巨细胞的频率增加，早期受照射细胞后代的放射敏感性增强。慢性低剂量照射不会诱导适应性反应。对莫斯科及切尔诺贝利灾难后受放射性核素污染地区（5 - 40居里/平方公里）居住的人群（成人和儿童）血液淋巴细胞中的适应性反应进行了比较研究。在受污染地区的人群中，具有明确适应性反应的个体频率降低，且有个体在条件剂量照射后放射敏感性增加。在受污染地区生活期间的慢性照射不会诱导适应性反应。
