Borodin Iu I, Astashov V V, Golubeva I A, Sklianova N A, Zagumennikov S Iu
Morfologiia. 1995;108(3):53-7.
Anterior mediastinal and popliteal lymph nodes were studied morphologically and cytologically in male Wistar line rats in an acute period of experimental ischemia resulting from ligation of the left coronary artery. Three stages of structural-functional changes were demonstrated. In first stage increase of cortical substance square, widening of intermediate sinuses and macrophage number increase in all lymph node zones were observed in both groups after ligation of the artery. Second stage (day III of the ischemia) is characterized with the accumulation of plasmatic series cells and reaction of blast transformation in lymph node zones. In third stage (day 7 of the ischemia) restoration of medullar sinuses square up to the control values and even certain increase of the latter were observed. Morphofunctional changes in an acute period of the experimental ischemia of myocardium depend on the lymph node functional specialization and they are greater expressed in mediastinal lymph nodes of the heart region. It was suggested that in an acute period of ischemia of myocardium lymph nodes influence the quantity and cellular content of the passing lymph.
对雄性Wistar系大鼠在左冠状动脉结扎导致实验性缺血急性期的前纵隔和腘淋巴结进行了形态学和细胞学研究。结果显示出三个结构 - 功能变化阶段。在第一阶段，动脉结扎后两组的皮质物质面积均增加，中间窦增宽，且所有淋巴结区域的巨噬细胞数量增多。第二阶段（缺血第三天）的特征是血浆系列细胞在淋巴结区域积聚以及发生母细胞转化反应。在第三阶段（缺血第七天），观察到髓窦面积恢复至对照值，甚至有所增加。心肌实验性缺血急性期的形态功能变化取决于淋巴结的功能特化，且在心脏区域的纵隔淋巴结中表现更为明显。研究表明，在心肌缺血急性期，淋巴结会影响通过的淋巴液的数量和细胞成分。
