Baillie R A, Jump D B, Clarke S D
Department of Human Ecology, University of Texas, Austin 78712, USA.
Curr Opin Lipidol. 1996 Feb;7(1):53-5. doi: 10.1097/00041433-199602000-00012.
Dietary polyunsaturated fatty acids modulate the transcription of numerous proteins including several hepatic lipogenic enzymes. Several lines of evidence indicate that polyunsaturated fatty acids do not regulate the transcription of hepatic lipogenic genes via a peroxisomal proliferator-activated receptor, but the mechanism may involve transcription factors related to the carbohydrate response region.
膳食多不饱和脂肪酸可调节众多蛋白质的转录,包括几种肝脏脂肪生成酶。多项证据表明,多不饱和脂肪酸并非通过过氧化物酶体增殖物激活受体来调节肝脏脂肪生成基因的转录,但其机制可能涉及与碳水化合物反应区域相关的转录因子。